Basic information
Locus name	AT1G76680
Alias	OPR1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Hormone response pathway:SA
Effect for Senescence	unclear
Gene Description	Encodes a member of an alpha/beta barrel fold family of FMN-containing oxidoreductases. One of the closely related 12-oxophytodienoic acid reductases. This enzyme is not expected to participate in jasmonic acid biosynthesis because during in vitro assays, it shows very little activity with the naturally occurring OPDA isomer. Shows activity towards 2,4,6-trinitrotoluene. Expressed predominately in root. Up-regulated by senescence and jasmonic acid. Induced by salicylic acid. Independent of NPR1 for their induction by salicylic acid. Predicted to be a cytosolic protein.
Evidence	Molecular evidence:Northern [Ref 1]
References	1: Morris K, MacKerness SA, Page T, John CF, Murphy AM, Carr JP, Buchanan-Wollaston V Salicylic acid has a role in regulating gene expression during leaf senescence. Plant J. 2000 Sep;23(5):677-85
Gene Ontology	biological process oxidation-reduction process molecular function FMN binding oxidoreductase activity
Sequence	AT1G76680.1 | Genomic | mRNA | CDS | Protein AT1G76680.2 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_126789	Accession Taxon NP_001077884 Arabidopsis thaliana NP_177794 Arabidopsis thaliana NP_177795 Arabidopsis thaliana NP_178662 Arabidopsis thaliana NP_973431 Arabidopsis thaliana NP_974157 ( AT1G76680 ) Arabidopsis thaliana 121264 Chlamydomonas reinhardtii 132041 Chlamydomonas reinhardtii 192522 Chlamydomonas reinhardtii NP_001047148 Oryza sativa Japonica Group NP_001057139 Oryza sativa Japonica Group NP_001057140 Oryza sativa Japonica Group NP_001057141 Oryza sativa Japonica Group NP_001057144 Oryza sativa Japonica Group NP_001057145 Oryza sativa Japonica Group NP_001061975 Oryza sativa Japonica Group e_gw1.326.36.1 Physcomitrella patens subsp. patens e_gw1.93.132.1 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_10231 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_620077 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_90063 Physcomitrella patens subsp. patens 29739.m003772 Ricinus communis 29907.m000654 Ricinus communis 34907.m000028 Ricinus communis XP_002951042 Volvox carteri f. nagariensis XP_002953576 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR22893 4.4E-255 4 369 No hit NA SUPERFAMILY SSF51395 2.2E-123 11 368 No hit NA Pfam PF00724 5.0E-88 12 345 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787