Basic information
Locus name	AT2G22810
Alias	ACS4
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Hormone response pathway:ET
Effect for Senescence	promote
Gene Description	key regulatory enzyme in the biosynthesis of the plant hormone ethylene.
Evidence	Genetic evidence:Mutant [Ref 1]
References	1: Tsuchisaka A, Yu G, Jin H, Alonso JM, Ecker JR, Zhang X, Gao S, Theologis A A combinatorial interplay among the 1-aminocyclopropane-1-carboxylate isoforms regulates ethylene biosynthesis in Arabidopsis thaliana. Genetics 2009 Nov;183(3):979-1003
Gene Ontology	biological process biosynthetic process molecular function catalytic activity pyridoxal phosphate binding
Pathway	Reactome REACT_13
Sequence	AT2G22810.1 | Genomic | mRNA | CDS | Protein
Mutant information
Mutant name	acs2-1acs4-1acs5-2acs6-1acs7-1acs9-1amiRacs8acs11
Mutant/Transgenic	mutant
Ecotype	Col-0
Mutagenesis type	cross
miRNA Interaction
Details	target: AT2G22810.1  miRNA: ath-miR5998a miRNA: ath-miR5998a mfe: -24.8 kcal/mol  p-value: 0.000000  position: 179  target 5' C        C        C    U 3'             ACAAAACA AGACGCAG CUGU                 UGUUUUGU UUUGUGUU GACA      miRNA  3'                   U      5'  target: AT2G22810.1  miRNA: ath-miR5998b miRNA: ath-miR5998b mfe: -24.8 kcal/mol  p-value: 0.000000  position: 179  target 5' C        C        C    U 3'             ACAAAACA AGACGCAG CUGU                 UGUUUUGU UUUGUGUU GACA      miRNA  3'                   U      5'  target: AT2G22810.1  miRNA: ath-miR843 miRNA: ath-miR843 mfe: -33.1 kcal/mol  p-value: 0.000000  position: 553  target 5' G                    C 3'             CCAA GAAGCUUGACCUAAA                 GGUU CUUCGAGCUGGAUUU      miRNA  3' A    A                 5'
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11751 1.3E-205 6 437 No hit NA SUPERFAMILY SSF53383 1.6E-96 8 426 IPR015424 Pyridoxal phosphate-dependent transferase Pfam PF00155 1.0E-95 41 425 IPR004839 Aminotransferase, class I/classII PRINTS PR00753 7.8E-104 43 69 No hit NA PRINTS PR00753 7.8E-104 76 92 No hit NA PRINTS PR00753 7.8E-104 113 133 No hit NA PRINTS PR00753 7.8E-104 135 156 No hit NA PRINTS PR00753 7.8E-104 189 213 No hit NA PRINTS PR00753 7.8E-104 226 249 No hit NA PRINTS PR00753 7.8E-104 264 288 No hit NA ProSitePatterns PS00105 NA 270 283 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site PRINTS PR00753 7.8E-104 296 319 No hit NA
Mutant Image
delayed flowering and senescence