Basic information
Locus name	AT1G32640
Alias	MYC2/JAI1/JIN1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Transcription regulation:MYC
Effect for Senescence	promote
Gene Description	JASMONATE INSENSITIVE 1;Encodes a MYC-related transcriptional activator with a typical DNA binding domain of a basic helix-loop-helix leucine zipper motif. Binds to an extended G-Box promoter motif and interacts with Jasmonate ZIM-domain proteins. Its transcription is induced by dehydration stress and ABA treatment. Negative regulator of blue light__ediated photomorphogenic growth and blue and far-red-light__egulated gene expression. Positive regulator of lateral root formation. Regulates diverse JA-dependent functions. Negatively regulates Trp metabolism and biosynthesis of Trp-derived secondary metabolites. Positively regulates flavonoid biosynthesis, resistance to insects, and response to oxidative stress. Regulates other transcription factors, and negatively regulates its own expression.
Evidence	Genetic evidence:Mutant [Ref 1]
References	1: Qi T, Wang J, Huang H, Liu B, Gao H, Liu Y, Song S, Xie D. Regulation of Jasmonate-Induced Leaf Senescence by Antagonism between bHLH Subgroup IIIe and IIId Factors in Arabidopsis. Plant Cell. 2015 Jun;27(6):1634-49. doi: 10.1105/tpc.15.00110. Epub 2015 Jun 12.
Gene Ontology	molecular function protein dimerization activity
Sequence	AT1G32640.1 | mRNA | CDS | Protein
Mutant information
Mutated 1 Mutant name MYC2OE Mutant/Transgenic transgene Ecotype Col-0 Mutagenesis type transgenic
Mutated 2 Mutant name myc2 myc3 myc4 Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type cross
Ortholog Group
Ortholog Groups: OG5_149804	Accession Taxon NP_174541 ( AT1G32640 ) Arabidopsis thaliana NP_193522 Arabidopsis thaliana NP_199488 Arabidopsis thaliana NP_001065478 Oryza sativa Japonica Group estExt_fgenesh1_pg.C_Chr_03.00010054 Ostreococcus tauri e_gw1.11.52.1 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_50104 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_740025 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_740028 Physcomitrella patens subsp. patens 29827.m002528 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11514 2.5E-256 1 623 No hit NA Pfam PF14215 1.3E-49 68 252 IPR025610 Transcription factor MYC/MYB N-terminal SUPERFAMILY SSF47459 7.1E-17 447 514 IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain ProSiteProfiles PS50888 17.1 448 497 IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain Pfam PF00010 3.9E-10 452 497 IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain SMART SM00353 8.2E-16 454 503 IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain Coils Coil NA 494 522 No hit NA
Mutant Image
Overexpression of MYC2, MYC3, and MYC4 Accelerates JA-Induced Leaf Senescence
Subcellular Localization
Localization	nucleus
Evidence	SUBAcon
Pubmed ID	23180787