Basic information
Locus name	AT1G05100
Alias	MAPKKK18
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Signal transduction
Effect for Senescence	promote
Gene Description	an Arabidopsis MAPKKK
Evidence	Molecular evidence [Ref 1]
References	1: Matsuoka D, Yasufuku T, Furuya T, Nanmori T. An abscisic acid inducible Arabidopsis MAPKKK, MAPKKK18 regulates leaf senescence via its kinase activity. Plant Mol Biol. 2015 Apr;87(6):565-75. doi: 10.1007/s11103-015-0295-0. Epub 2015 Feb 14.
Gene Ontology	biological process protein phosphorylation molecular function ATP binding protein kinase activity protein serine/threonine kinase activity
Sequence	AT1G05100.1 | mRNA | CDS | Protein
Mutant information
Mutated 1 Mutant name 35S:MAPKKK18 Mutant/Transgenic transgene Ecotype Col-0 Mutagenesis type transgenic
Mutated 2 Mutant name 35S:MAPKKK18KN Mutant/Transgenic transgene Ecotype Col-0 Mutagenesis type transgenic
Ortholog Group
Ortholog Groups: OG5_211865	Accession Taxon NP_172003 ( AT1G05100 ) Arabidopsis thaliana NP_180810 Arabidopsis thaliana
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR24361 4.2E-136 2 334 No hit NA SUPERFAMILY SSF56112 3.3E-73 2 296 IPR011009 Protein kinase-like domain ProSiteProfiles PS50011 41.1 3 263 IPR000719 Protein kinase, catalytic domain SMART SM00220 5.3E-71 3 263 IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain Pfam PF00069 4.3E-55 4 263 IPR000719 Protein kinase, catalytic domain ProSitePatterns PS00107 NA 9 32 IPR017441 Protein kinase, ATP binding site ProSitePatterns PS00108 NA 127 139 IPR008271 Serine/threonine-protein kinase, active site
Mutant Image
Senescence of the rosette leaves was promoted in 35S:MAPKKK18, but suppressed in 35S:MAPKKK18 KN