Basic information
Locus name	At3g50260
Alias	DEAR1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Transcription regulation:ERF
Effect for Senescence	promote
Gene Description	Encodes a member of the DREB subfamily A-5 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. Involved in defense and freezing stress responses. There are 16 members in this subfamily including RAP2.1, RAP2.9 and RAP2.10. The mRNA is cell-to-cell mobile.
Evidence	Genetic evidence:Mutant [Ref 1]
References	1: Tsutsui T, Kato W, Asada Y, Sako K, Sato T, Sonoda Y, Kidokoro S, Yamaguchi-Shinozaki K, Tamaoki M, Arakawa K, Ichikawa T, Nakazawa M, Seki M, Shinozaki K, Matsui M, Ikeda A, Yamaguchi J. DEAR1, a transcriptional repressor of DREB protein that mediates plant defense and freezing stress responses in Arabidopsis. J Plant Res. 2009 Nov;122(6):633-43. doi: 10.1007/s10265-009-0252-6. Epub 2009 Jul 18.
Gene Ontology	biological process regulation of transcription, DNA-dependent molecular function sequence-specific DNA binding transcription factor activity
Sequence	AT3G50260.1 | mRNA | CDS | Protein
Mutant information
Mutant name	35S::DEAR1
Mutant/Transgenic	transgene
Ecotype	Col-0
Mutagenesis type	transgenic
Ortholog Group
Ortholog Groups: OG5_160187	Accession Taxon NP_179915 Arabidopsis thaliana NP_190595 ( At3g50260 ) Arabidopsis thaliana NP_195408 Arabidopsis thaliana NP_201520 Arabidopsis thaliana NP_001047906 Oryza sativa Japonica Group NP_001054079 Oryza sativa Japonica Group 30170.m013843 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR31729 8.3E-72 1 152 No hit NA ProSiteProfiles PS51032 22.5 20 77 IPR001471 AP2/ERF domain SMART SM00380 1.4E-36 20 83 IPR001471 AP2/ERF domain Pfam PF00847 6.5E-15 21 69 IPR001471 AP2/ERF domain PRINTS PR00367 2.1E-8 21 32 IPR001471 AP2/ERF domain SUPERFAMILY SSF54171 5.1E-21 21 78 IPR016177 DNA-binding, integrase-type PRINTS PR00367 2.1E-8 43 59 IPR001471 AP2/ERF domain
Mutant Image
Overexpression of DEAR1 results in a cell death phenotype
Subcellular Localization
Localization	nucleus
Evidence	SUBAcon
Pubmed ID	23180787