Basic information
Locus name	AT4G35580
Alias	NTL9
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Transcription regulation:NAC
Effect for Senescence	promote
Gene Description	a membrane-associated NAC transcription factor, NTL9, mediates osmotic stress signaling in leaf senescence
Evidence	Genetic evidence:Mutant and transgene [Ref 1]; Genomice evidence: microarray data [Ref 2]
References	1: Yoon HK, Kim SG, Kim SY, Park CM Regulation of leaf senescence by NTL9-mediated osmotic stress signaling in Arabidopsis. Mol. Cells 2008 May 31;25(3):438-45 2: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process regulation of transcription, DNA-dependent molecular function DNA binding
Sequence	AT4G35580.1 | Genomic | mRNA | CDS | Protein AT4G35580.2 | Genomic | mRNA | CDS | Protein
Mutant information
Mutated 1 Mutant name ntl9-1 Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type T-DNA insertion_knock out
Mutated 2 Mutant name 35S::9 deltaC transgenic plant Mutant/Transgenic transgenic Ecotype Col-0 Mutagenesis type transgene
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT4G35580.1  miRNA: ath-miR839 miRNA: ath-miR839 mfe: -31.9 kcal/mol  p-value: 0.000418  position:  1506  target 5' A   A                 U 3'             GGG AGCGAUGGAAGG UGGU              CCC UUGCUACUUUCC ACCA   miRNA  3'                  A    U 5'  target: AT4G35580.2  miRNA: ath-miR839 miRNA: ath-miR839 mfe: -31.9 kcal/mol  p-value: 0.000425  position:  1525  target 5' A   A                 U 3'             GGG AGCGAUGGAAGG UGGU              CCC UUGCUACUUUCC ACCA   miRNA  3'                  A    U 5'
Ortholog Group
Ortholog Groups: OG5_160072	Accession Taxon NP_001119122 ( AT4G35580 ) Arabidopsis thaliana NP_174582 Arabidopsis thaliana NP_567986 Arabidopsis thaliana NP_973954 Arabidopsis thaliana NP_001056531 Oryza sativa Japonica Group NP_001061034 Oryza sativa Japonica Group 30068.m002619 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR31989 5.8E-117 1 472 No hit NA SUPERFAMILY SSF101941 8.0E-64 4 159 IPR003441 No apical meristem (NAM) protein Pfam PF02365 1.1E-51 9 135 IPR003441 No apical meristem (NAM) protein ProSiteProfiles PS51005 58.0 9 159 IPR003441 No apical meristem (NAM) protein