Basic information
Locus name	AT4G18880
Alias	HSF21
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Transcription regulation:HSF
Effect for Senescence	unclear
Gene Description	heat shock transcription factor 21 (HSF21)
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process regulation of transcription, DNA-dependent cellular component nucleus molecular function sequence-specific DNA binding transcription factor activity sequence-specific DNA binding
Sequence	AT4G18880.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT4G18880.1  miRNA: ath-miR415 miRNA: ath-miR415 mfe: -27.9 kcal/mol  p-value: 0.001335  position:  412  target 5' U  C          G       U 3'             UG UCUGUUUUUG CUCUGUU              AC AGACAAAGAC GAGACAA   miRNA  3' U  A                    5'  target: AT4G18880.1  miRNA: ath-miR867 miRNA: ath-miR867 mfe: -23.5 kcal/mol  p-value: 0.018023  position:  1160  target 5' U    C         A    G  A 3'             UUCC GAUGAACCG UGUU GA              AAGG UUAUUUGGU ACAA UU   miRNA  3'      A              G    5'
Ortholog Group
Ortholog Groups: OG5_129203	Accession Taxon NP_191894 Arabidopsis thaliana NP_193623 ( AT4G18880 ) Arabidopsis thaliana NP_195416 Arabidopsis thaliana NP_113340 Guillardia theta e_gw1.20.00.75.1 Ostreococcus tauri estExt_Genewise1.C_310312 Physcomitrella patens subsp. patens gw1.42.207.1 Physcomitrella patens subsp. patens 29636.m000750 Ricinus communis 30026.m001484 Ricinus communis estExt_fgenesh1_pg.C_chr_100042 Thalassiosira pseudonana CCMP1335
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR10015 3.4E-94 11 192 No hit NA SUPERFAMILY SSF46785 4.1E-35 11 105 No hit NA SMART SM00415 7.6E-63 12 105 IPR000232 Heat shock factor (HSF)-type, DNA-binding Pfam PF00447 3.8E-32 16 107 IPR000232 Heat shock factor (HSF)-type, DNA-binding PRINTS PR00056 5.3E-19 16 39 IPR000232 Heat shock factor (HSF)-type, DNA-binding PRINTS PR00056 5.3E-19 54 66 IPR000232 Heat shock factor (HSF)-type, DNA-binding PRINTS PR00056 5.3E-19 67 79 IPR000232 Heat shock factor (HSF)-type, DNA-binding SUPERFAMILY SSF58113 7.1E-5 96 187 No hit NA Coils Coil NA 128 177 No hit NA
Subcellular Localization
Localization	nucleus
Evidence	SUBAcon
Pubmed ID	23180787