Basic information
Locus name	AT1G06570
Alias	PDS1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Redox regulation:Antioxidants
Effect for Senescence	unclear
Gene Description	PHYTOENE DESATURATION 1 (PDS1); FUNCTIONS IN: 4-hydroxyphenylpyruvate dioxygenase activity; INVOLVED IN: carotenoid biosynthetic process, plastoquinone biosynthetic process, vitamin E biosynthetic process. Gene expression is increased during leaf senescence.
Evidence	Genomic evidence:microarray data [Ref 1, Ref 2]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85 2: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process aromatic amino acid family metabolic process oxidation-reduction process molecular function 4-hydroxyphenylpyruvate dioxygenase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
Sequence	AT1G06570.1 | Genomic | mRNA | CDS | Protein AT1G06570.2 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT1G06570.1  miRNA: ath-miR835-5p miRNA: ath-miR835-5p mfe: -20.3 kcal/mol  p-value: 0.038231  position:  1023  target 5' A             U     C 3'             GUGAAGA CAUAU CAGGA              UAUUUCU GUAUA GUUCU   miRNA  3' C       U     C     U 5'  target: AT1G06570.2  miRNA: ath-miR835-5p miRNA: ath-miR835-5p mfe: -20.3 kcal/mol  p-value: 0.038078  position:  1023  target 5' A             U     C 3'             GUGAAGA CAUAU CAGGA              UAUUUCU GUAUA GUUCU   miRNA  3' C       U     C     U 5'
Ortholog Group
Ortholog Groups: OG5_129448	Accession Taxon NP_001154311 Arabidopsis thaliana NP_172144 ( AT1G06570 ) Arabidopsis thaliana CMI063C Cyanidioschyzon merolae strain 10D 137761 Chlamydomonas reinhardtii 149028 Chlamydomonas reinhardtii ACO60639 Micromonas sp. RCC299 NP_001046010 Oryza sativa Japonica Group e_gw1.03.00.251.1 Ostreococcus tauri estExt_Genewise1.C_210075 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_300146 Physcomitrella patens subsp. patens 29993.m001037 Ricinus communis e_gw1.2.221.1 Thalassiosira pseudonana CCMP1335 XP_002952694 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11959 1.3E-142 48 472 IPR005956 4-hydroxyphenylpyruvate dioxygenase SUPERFAMILY SSF54593 3.2E-96 64 456 No hit NA TIGRFAM TIGR01263 2.5E-112 74 467 IPR005956 4-hydroxyphenylpyruvate dioxygenase Pfam PF00903 1.1E-5 251 407 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain
Subcellular Localization
Localization 1 Localization cytosol Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization cytosol Evidence SUBAcon Pubmed ID 23180787
Localization 3 Localization mitochondrion Evidence SUBAcon Pubmed ID 23180787