Leaf Senescence DataBase

Basic information

Locus name

AT1G01480

Alias

ACS2

Organism

Arabidopsis thaliana

Taxonomic identifier

[NCBI]

Function category

Hormone response pathway:ET

Effect for Senescence

promote

Gene Description

1-aminocyclopropane-1-carboxylate synthase 2 / ACC synthase 2 (ACS2) (ACC1) identical to 1-aminocyclopropane-1-carboxylate synthase SP|Q06402 [GI:166578] from [Arabidopsis thaliana]

Evidence

Genomic evidence:microarray data [Ref 1, Ref 2]

References

1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ
Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis.
Plant J. 2005 May;42(4):567-85

2: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston
High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation.
Plant Cell 2011 Mar;23(3):873-94

Gene Ontology

biological process	biosynthetic process
molecular function	catalytic activity pyridoxal phosphate binding

Pathway

Reactome

REACT_13

Sequence

Mutant information

Mutant name

acs2-1acs4-1acs5-2acs6-1acs7-1acs9-1amiRacs8acs11

Mutant/Transgenic

mutant

Ecotype

Col-0

Mutagenesis type

cross

Microarray

Sampling

Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ.
Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis.
Plant J. 2005 May;42(4)

Comparation

Legends:
Col: wild type, indicates the ratio of expression in senescing leaves/green leaves.
NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type.
D/L: ratio of DARK 5d/control.
Genes showing at least 3 fold (ratio) up regulation during leaf senescence.

miRNA Interaction

Details

target: AT1G01480.1
miRNA: ath-miR1886
miRNA: ath-miR1886
mfe: -22.7 kcal/mol
p-value: 0.017700

position:  1370
target 5' A G    C          G  U 3'
           C GAUC AAGAUUUCGU UC
           G UUAG UUCUAAAGUA AG
miRNA  3'   G    U          G  U 5'

target: AT1G01480.1
miRNA: ath-miR394a
miRNA: ath-miR394a
mfe: -27.9 kcal/mol
p-value: 0.015851

position:  561
target 5' A  U  C              G 3'
           GG GG GGACAGG UGUCGA
           CC CC CCUGUCU ACGGUU
miRNA  3'    U  A       U        5'

target: AT1G01480.1
miRNA: ath-miR394b
miRNA: ath-miR394b
mfe: -27.9 kcal/mol
p-value: 0.012351

position:  561
target 5' A  U  C              G 3'
           GG GG GGACAGG UGUCGA
           CC CC CCUGUCU ACGGUU
miRNA  3'    U  A       U        5'

target: AT1G01480.1
miRNA: ath-miR396a
miRNA: ath-miR396a
mfe: -26.6 kcal/mol
p-value: 0.010073

position:  1085
target 5' A  C                 U 3'
           AG UCGAGAAGGUUG GGGA
           UC AGUUCUUUCGAC CCUU
miRNA  3' G  A            A      5'

target: AT1G01480.1
miRNA: ath-miR396b
miRNA: ath-miR396b
mfe: -26.8 kcal/mol
p-value: 0.010323

position:  1084
target 5' A   C                 U 3'
           AAG UCGAGAAGGUUG GGGA
           UUC AGUUCUUUCGAC CCUU
miRNA  3'     A            A      5'

target: AT1G01480.2
miRNA: ath-miR1886
miRNA: ath-miR1886
mfe: -22.7 kcal/mol
p-value: 0.015469

position:  1185
target 5' A G    C          G  U 3'
           C GAUC AAGAUUUCGU UC
           G UUAG UUCUAAAGUA AG
miRNA  3'   G    U          G  U 5'

target: AT1G01480.2
miRNA: ath-miR394a
miRNA: ath-miR394a
mfe: -27.9 kcal/mol
p-value: 0.014266

position:  376
target 5' A  U  C              G 3'
           GG GG GGACAGG UGUCGA
           CC CC CCUGUCU ACGGUU
miRNA  3'    U  A       U        5'

target: AT1G01480.2
miRNA: ath-miR394b
miRNA: ath-miR394b
mfe: -27.9 kcal/mol
p-value: 0.010901

position:  376
target 5' A  U  C              G 3'
           GG GG GGACAGG UGUCGA
           CC CC CCUGUCU ACGGUU
miRNA  3'    U  A       U        5'

target: AT1G01480.2
miRNA: ath-miR396a
miRNA: ath-miR396a
mfe: -26.6 kcal/mol
p-value: 0.008666

position:  900
target 5' A  C                 U 3'
           AG UCGAGAAGGUUG GGGA
           UC AGUUCUUUCGAC CCUU
miRNA  3' G  A            A      5'

target: AT1G01480.2
miRNA: ath-miR396b
miRNA: ath-miR396b
mfe: -26.8 kcal/mol
p-value: 0.009019

position:  899
target 5' A   C                 U 3'
           AAG UCGAGAAGGUUG GGGA
           UUC AGUUCUUUCGAC CCUU
miRNA  3'     A            A      5'

Ortholog Group

Ortholog Groups: OG5_128619

Accession	Taxon
NP_171655 ( AT1G01480 )	Arabidopsis thaliana
NP_179866	Arabidopsis thaliana
NP_190539	Arabidopsis thaliana
NP_191710	Arabidopsis thaliana
NP_192867	Arabidopsis thaliana
NP_194350	Arabidopsis thaliana
NP_195491	Arabidopsis thaliana
NP_199982	Arabidopsis thaliana
NP_201381	Arabidopsis thaliana
NP_564804	Arabidopsis thaliana
NP_567330	Arabidopsis thaliana
NP_849572	Arabidopsis thaliana
CMS398C	Cyanidioschyzon merolae strain 10D
170056	Chlamydomonas reinhardtii
ACO63161	Micromonas sp. RCC299
NP_001042279	Oryza sativa Japonica Group
NP_001051142	Oryza sativa Japonica Group
NP_001053637	Oryza sativa Japonica Group
NP_001056689	Oryza sativa Japonica Group
e_gw1.08.00.217.1	Ostreococcus tauri
e_gw1.376.41.1	Physcomitrella patens subsp. patens
estExt_gwp_gw1.C_2350048	Physcomitrella patens subsp. patens
fgenesh1_pg.scaffold_46000126	Physcomitrella patens subsp. patens
29825.m000323	Ricinus communis
29912.m005403	Ricinus communis
30147.m014167	Ricinus communis
30170.m013658	Ricinus communis
30174.m008659	Ricinus communis
30190.m011061	Ricinus communis
30190.m011272	Ricinus communis
e_gw1.1.386.1	Thalassiosira pseudonana CCMP1335
gw1.18.45.1	Thalassiosira pseudonana CCMP1335
XP_002946823	Volvox carteri f. nagariensis

Cross Link

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PANTHER	PTHR11751	1.3E-219	1	381	No hit	NA
SUPERFAMILY	SSF53383	3.0E-88	3	331	IPR015424	Pyridoxal phosphate-dependent transferase
Pfam	PF00155	5.4E-93	5	326	IPR004839	Aminotransferase, class I/classII
PRINTS	PR00753	1.9E-81	15	35	No hit	NA
PRINTS	PR00753	1.9E-81	37	58	No hit	NA
PRINTS	PR00753	1.9E-81	91	115	No hit	NA
PRINTS	PR00753	1.9E-81	127	150	No hit	NA
PRINTS	PR00753	1.9E-81	164	188	No hit	NA
ProSitePatterns	PS00105	NA	170	183	IPR004838	Aminotransferases, class-I, pyridoxal-phosphate-binding site
PRINTS	PR00753	1.9E-81	196	219	No hit	NA

Mutant Image

delayed flowering and senescence