Basic information
GenBank ID	AF022716
Alias	GMP
Organism	Potato (Solanum tuberosum)
Taxonomic identifier	[NCBI]
Function category	Lipid/Carbohydrate metabolism
Effect for Senescence	delay
Gene Description	GDP-mannose pyrophosphorylase (GMPase, EC 2.7.7.22) catalyses the synthesis of GDP-D-mannose and represents the first committed step in the formation of all guanosin-containing sugar nucleotides found in plants which are precursors for cell wall biosynthesis and, probably more important, the synthesis of ascorbate.
Evidence	Genetic evidence:Transgene [Ref 1]
References	1: Keller R, Renz FS, Kossmann J Antisense inhibition of the GDP-mannose pyrophosphorylase reduces the ascorbate content in transgenic plants leading to developmental changes during senescence. Plant J. 1999 Jul;19(2):131-41
Gene Ontology	biological process biosynthetic process molecular function nucleotidyltransferase activity
Pathway	Reactome REACT_17015
Sequence	AF022716.1 | mRNA | CDS | Protein
Mutant information
Mutant name	GMP-RNAi
Mutant/Transgenic	transgenic
Ecotype	Potato
Mutagenesis type	RNAi
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR22572 1.6E-172 1 361 No hit NA SUPERFAMILY SSF53448 2.4E-73 1 312 No hit NA Pfam PF00483 7.0E-49 2 228 IPR005835 Nucleotidyl transferase Pfam PF00132 2.4E-6 255 287 IPR001451 Bacterial transferase hexapeptide repeat