|
|
Locus name | AT1G11190 |
Alias | BFN1 | Organism | Arabidopsis thaliana | Taxonomic identifier | [NCBI] | Function category | Nucleic acid degradation:RNA and DNA degradation | Effect for Senescence | Unclear | Gene Description | Encodes a bifunctional nuclease that acts on both RNA and DNA involved in nucleic acid degradation to facilitate nucleotide and phosphate recovery during senescence. It has mismatch-specific endonuclease activity with wide recognition of single base mismatches as well as the ability to cleave indel types of mismatches (heteroduplexes with loops). | Evidence | Molecular evidence:Northern and GUS staining [Ref 1, Ref 2]; Genomic evidence: microarray data [Ref 3, Ref 4] | References | 1: Perez-Amador MA, Abler ML, De Rocher EJ, Thompson DM, van Hoof A, LeBrasseur ND, Lers A, Green PJIdentification of BFN1, a bifunctional nuclease induced during leaf and stem senescence in Arabidopsis.Plant Physiol. 2000 Jan;122(1):169-802: Farage-Barhom S, Burd S, Sonego L, Perl-Treves R, Lers AExpression analysis of the BFN1 nuclease gene promoter during senescence, abscission, and programmed cell death-related processes.J. Exp. Bot. 2008;59(12):3247-583: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJComparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis.Plant J. 2005 May;42(4):567-854: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-WollastonHigh-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation.Plant Cell 2011 Mar;23(3):873-94 | Gene Ontology | | Sequence | AT1G11190.1 | Genomic | mRNA | CDS | Protein
|
| Sampling |
Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4) | Comparation |
Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence. |
miRNA Interaction | |
| Details | | target: AT1G11190.1 miRNA: ath-miR156a miRNA: ath-miR156a mfe: -30.9 kcal/mol p-value: 0.001575
position: 143 target 5' U G C 3' GUGUUCG UUUCUUCUGUC CACGAGU AGAGAAGACAG miRNA 3' G U 5'
target: AT1G11190.1 miRNA: ath-miR156b miRNA: ath-miR156b mfe: -30.9 kcal/mol p-value: 0.001155
position: 143 target 5' U G C 3' GUGUUCG UUUCUUCUGUC CACGAGU AGAGAAGACAG miRNA 3' G U 5'
target: AT1G11190.1 miRNA: ath-miR156c miRNA: ath-miR156c mfe: -30.9 kcal/mol p-value: 0.001516
position: 143 target 5' U G C 3' GUGUUCG UUUCUUCUGUC CACGAGU AGAGAAGACAG miRNA 3' G U 5'
target: AT1G11190.1 miRNA: ath-miR156d miRNA: ath-miR156d mfe: -30.9 kcal/mol p-value: 0.001665
position: 143 target 5' U G C 3' GUGUUCG UUUCUUCUGUC CACGAGU AGAGAAGACAG miRNA 3' G U 5'
target: AT1G11190.1 miRNA: ath-miR156e miRNA: ath-miR156e mfe: -30.9 kcal/mol p-value: 0.001065
position: 143 target 5' U G C 3' GUGUUCG UUUCUUCUGUC CACGAGU AGAGAAGACAG miRNA 3' G U 5'
target: AT1G11190.1 miRNA: ath-miR156f miRNA: ath-miR156f mfe: -30.9 kcal/mol p-value: 0.001585
position: 143 target 5' U G C 3' GUGUUCG UUUCUUCUGUC CACGAGU AGAGAAGACAG miRNA 3' G U 5'
target: AT1G11190.1 miRNA: ath-miR156g miRNA: ath-miR156g mfe: -31.2 kcal/mol p-value: 0.000873
position: 143 target 5' U G C 3' GUGUUCG UUUCUUCUGUC CACGAGU AGAGAAGACAG miRNA 3' G C 5'
|
|
Ortholog Group | |
| Ortholog Groups: OG5_128720 | |
Cross Link | |
| |
| Localization | extracellular | Evidence | SUBAcon | Pubmed ID | 23180787 |
|