Basic information
Locus name	AT2G19570
Alias	CDD
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Nucleic acid degradation
Effect for Senescence	unclear
Gene Description	cytidine deaminase (CDD) / cytidine aminohydrolase identical to cytidine deaminase (CDD) [Arabidopsis thaliana] GI:3046700
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process cytidine deamination molecular function cytidine deaminase activity hydrolase activity zinc ion binding
Pathway	KEGG map00240 (EC 3.5.4.5) map00983 (EC 3.5.4.5) MetaCyc PWY-6556
Sequence	AT2G19570.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT2G19570.1  miRNA: ath-miR399a miRNA: ath-miR399a mfe: -29.3 kcal/mol  p-value: 0.003382  position:  307  target 5' U    U           A    U 3'             CAGG CGGAUCUUCUU GGCG              GUCC GUUUAGAGGAA CCGU   miRNA  3'      C           A      5'  target: AT2G19570.1  miRNA: ath-miR831 miRNA: ath-miR831 mfe: -26.4 kcal/mol  p-value: 0.009808  position:  904  target 5' G       A      A      U 3'             GAGGAGG UACGAG GGAUCG              UUCUUCU AUGCUU UCUAGU   miRNA  3' G       C      C        5'
Ortholog Group
Ortholog Groups: OG5_127381	Accession Taxon NP_179547 ( AT2G19570 ) Arabidopsis thaliana CMR254C Cyanidioschyzon merolae strain 10D 127415 Chlamydomonas reinhardtii ACO61475 Micromonas sp. RCC299 NP_001044051 Oryza sativa Japonica Group gw1.05.00.335.1 Ostreococcus tauri e_gw1.45.82.1 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_20023 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_4820001 Physcomitrella patens subsp. patens 29912.m005381 Ricinus communis 33255.m000017 Ricinus communis XP_002949245 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11644 1.5E-169 1 299 No hit NA PIRSF PIRSF006334 3.3E-159 1 298 IPR006263 Cytidine deaminase, homodimeric TIGRFAM TIGR01355 1.0E-138 4 299 IPR006263 Cytidine deaminase, homodimeric SUPERFAMILY SSF53927 3.4E-29 8 122 IPR016193 Cytidine deaminase-like Pfam PF00383 4.2E-10 36 115 IPR002125 CMP/dCMP deaminase, zinc-binding ProSitePatterns PS00903 NA 77 111 IPR016192 APOBEC/CMP deaminase, zinc-binding SUPERFAMILY SSF53927 4.5E-30 144 288 IPR016193 Cytidine deaminase-like Pfam PF08211 2.1E-48 145 282 IPR013171 Cytidine/deoxycytidylate deaminase, zinc-binding domain
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787