Basic information
Locus name	AT2G42620
Alias	ORE9/MAX2/PPS
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Protein degradation/modification:F-box
Effect for Senescence	promote
Gene Description	The mutations at MAX2 cause increased hypocotyl and petiole elongation in light-grown seedlings. Positional cloning identifies MAX2 as a member of the F-box leucine-rich repeat family of proteins. MAX2 is identical to ORE9, a proposed regulator of leaf senescence. Involved in positive regulation of light responses.
Evidence	Genetic evidence:Mutant [Ref 1, Ref 2, Ref 3, Ref 4, Ref 5, Ref 6, Ref 7]
References	1: Woo HR, Chung KM, Park JH, Oh SA, Ahn T, Hong SH, Jang SK, Nam HG ORE9, an F-box protein that regulates leaf senescence in Arabidopsis. Plant Cell 2001 Aug;13(8):1779-90 2: Shen H, Luong P, Huq E The F-box protein MAX2 functions as a positive regulator of photomorphogenesis in Arabidopsis. Plant Physiol. 2007 Dec;145(4):1471-83 3: Yan H, Saika H, Maekawa M, Takamure I, Tsutsumi N, Kyozuka J, Nakazono M Rice tillering dwarf mutant dwarf3 has increased leaf longevity during darkness-induced senescence or hydrogen peroxide-induced cell death. Genes Genet. Syst. 2007 Aug;82(4):361-6 4: Stirnberg P, Furner IJ, Ottoline Leyser HM MAX2 participates in an SCF complex which acts locally at the node to suppress shoot branching. Plant J. 2007 Apr;50(1):80-94 5: Tang D, Christiansen KM, Innes RW Regulation of plant disease resistance, stress responses, cell death, and ethylene signaling in Arabidopsis by the EDR1 protein kinase. Plant Physiol. 2005 Jun;138(2):1018-26 6: Ishikawa S, Maekawa M, Arite T, Onishi K, Takamure I, Kyozuka J Suppression of tiller bud activity in tillering dwarf mutants of rice. Plant Cell Physiol. 2005 Jan;46(1):79-86 7: Stirnberg P, van De Sande K, Leyser HM MAX1 and MAX2 control shoot lateral branching in Arabidopsis. Development 2002 Mar;129(5):1131-41
Sequence	AT2G42620.1 | Genomic | mRNA | CDS | Protein
Mutant information
Mutant name	ore9-1
Mutant/Transgenic	mutant
Ecotype	Col-0
Mutagenesis type	EMS
miRNA Interaction
Details	target: AT2G42620.1  miRNA: ath-miR172b miRNA: ath-miR172b mfe: -24.4 kcal/mol  p-value: 0.010642  position:  936  target 5' U     G A         A  U 3'             GUGAA C UAGUGGUGU GC              CACUU G AUUACCACG CG   miRNA  3'       A A         A    5'  target: AT2G42620.1  miRNA: ath-miR782 miRNA: ath-miR782 mfe: -28.4 kcal/mol  p-value: 0.005407  position:  1004  target 5' U      G U            C 3'             AGGACA U CCAAGGUGUUUG              UCUUGU A GGUUCCACAAAC   miRNA  3' U                     A 5'
Ortholog Group
Ortholog Groups: OG5_190918	Accession Taxon NP_565979 ( AT2G42620 ) Arabidopsis thaliana estExt_gwp_gw1.C_1480025 Physcomitrella patens subsp. patens 29682.m000601 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR23125 1.1E-30 4 434 No hit NA SUPERFAMILY SSF52047 5.9E-17 66 223 No hit NA SMART SM00367 470.0 215 246 IPR006553 Leucine-rich repeat, cysteine-containing subtype SUPERFAMILY SSF52047 5.9E-17 275 431 No hit NA SMART SM00367 0.4 346 371 IPR006553 Leucine-rich repeat, cysteine-containing subtype SMART SM00367 27.0 372 397 IPR006553 Leucine-rich repeat, cysteine-containing subtype
Mutant Image
ore9 mutant exhibited delay senescence
Subcellular Localization
Localization 1 Localization other cytoplasmic components Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization plastid Evidence SUBAcon Pubmed ID 23180787