Basic information
Locus name	AT1G18870
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others:Defence related
Effect for Senescence	unclear
Gene Description	isochorismate synthase, putative / isochorismate mutase, putative similar to GI:17223087
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process biosynthetic process molecular function isochorismate synthase activity
Pathway	KEGG map00130 (EC 5.4.4.2) MetaCyc PWY-5837
Sequence	AT1G18870.1 | Genomic | mRNA | CDS | Protein AT1G18870.2 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT1G18870.1  miRNA: ath-miR835-5p miRNA: ath-miR835-5p mfe: -22.8 kcal/mol  p-value: 0.014485  position:  1515  target 5' U      G          U   C 3'             GAUAGA GAAUGUAUGC GGA              CUAUUU CUUGUAUACG UCU   miRNA  3'                   U   U 5'  target: AT1G18870.2  miRNA: ath-miR835-5p miRNA: ath-miR835-5p mfe: -22.8 kcal/mol  p-value: 0.013679  position:  1410  target 5' U      G          U   C 3'             GAUAGA GAAUGUAUGC GGA              CUAUUU CUUGUAUACG UCU   miRNA  3'                   U   U 5'
Ortholog Group
Ortholog Groups: OG5_132914	Accession Taxon NP_001154351 Arabidopsis thaliana NP_173321 ( AT1G18870 ) Arabidopsis thaliana NP_565090 Arabidopsis thaliana NP_974143 Arabidopsis thaliana CMV114C Cyanidioschyzon merolae strain 10D 120595 Chlamydomonas reinhardtii NP_001062984 Oryza sativa Japonica Group e_gw1.24.30.1 Physcomitrella patens subsp. patens 30147.m014077 Ricinus communis thaps1_ua_kg.chr_8000085 Thalassiosira pseudonana CCMP1335 XP_002954494 Volvox carteri f. nagariensis XP_002954495 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11236 5.5E-276 1 512 No hit NA SUPERFAMILY SSF56322 9.6E-82 74 504 IPR005801 ADC synthase TIGRFAM TIGR00543 1.9E-114 144 502 IPR004561 Isochorismate synthase Coils Coil NA 203 224 No hit NA Pfam PF00425 1.4E-59 239 494 IPR015890 Chorismate binding, C-terminal
Subcellular Localization
Localization	plastid
Evidence	SUBAcon
Pubmed ID	23180787