Basic information
Locus name	AT3G12580
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others:stress and detoxification
Effect for Senescence	unclear
Gene Description	heat shock protein 70, putative / HSP70, putative strong similarity to heat shock protein GI:425194 [Spinacia oleracea]
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Sequence	AT3G12580.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT3G12580.1  miRNA: ath-miR169g miRNA: ath-miR169g mfe: -30.9 kcal/mol  p-value: 0.005141  position:  774  target 5' A                    U 3'             AGUCAAGG CAACU GCUGG              UCGGUUCC GUUGA CGGCC   miRNA  3'          A     A     U 5'
Ortholog Group
Ortholog Groups: OG5_126588	Accession Taxon NP_001119156 Arabidopsis thaliana NP_172382 Arabidopsis thaliana NP_173055 Arabidopsis thaliana NP_176036 Arabidopsis thaliana NP_187555 Arabidopsis thaliana NP_187864 ( AT3G12580 ) Arabidopsis thaliana NP_195869 Arabidopsis thaliana NP_195870 Arabidopsis thaliana NP_198206 Arabidopsis thaliana NP_199017 Arabidopsis thaliana NP_851119 Arabidopsis thaliana CMP145C Cyanidioschyzon merolae strain 10D CMT579C Cyanidioschyzon merolae strain 10D 133650 Chlamydomonas reinhardtii 133859 Chlamydomonas reinhardtii 185673 Chlamydomonas reinhardtii NP_113319 Guillardia theta ACO63925 Micromonas sp. RCC299 ACO68376 Micromonas sp. RCC299 NP_001044757 Oryza sativa Japonica Group NP_001045675 Oryza sativa Japonica Group NP_001049712 Oryza sativa Japonica Group NP_001049715 Oryza sativa Japonica Group NP_001049719 Oryza sativa Japonica Group NP_001051048 Oryza sativa Japonica Group NP_001051724 Oryza sativa Japonica Group NP_001055339 Oryza sativa Japonica Group NP_001055613 Oryza sativa Japonica Group NP_001055754 Oryza sativa Japonica Group NP_001061194 Oryza sativa Japonica Group NP_001067408 Oryza sativa Japonica Group NP_001068540 Oryza sativa Japonica Group e_gw1.02.00.90.1 Ostreococcus tauri e_gw1.17.00.27.1 Ostreococcus tauri estExt_Genewise1.C_1810001 Physcomitrella patens subsp. patens estExt_Genewise1.C_3510021 Physcomitrella patens subsp. patens estExt_Genewise1.C_390053 Physcomitrella patens subsp. patens estExt_Genewise1.C_5260001 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_20112 Physcomitrella patens subsp. patens fgenesh1_pg.scaffold_288000014 Physcomitrella patens subsp. patens fgenesh1_pg.scaffold_298000015 Physcomitrella patens subsp. patens fgenesh1_pm.scaffold_91000017 Physcomitrella patens subsp. patens fgenesh2_pg.scaffold_97000105 Physcomitrella patens subsp. patens 29585.m000574 Ricinus communis 29887.m000234 Ricinus communis 30025.m000589 Ricinus communis 30068.m002531 Ricinus communis 30073.m002215 Ricinus communis 30131.m006880 Ricinus communis 30131.m006881 Ricinus communis e_gw1.22.27.1 Thalassiosira pseudonana CCMP1335 estExt_Genewise1.C_chr_30700 Thalassiosira pseudonana CCMP1335 estExt_thaps1_ua_kg.C_chr_60235 Thalassiosira pseudonana CCMP1335 thaps1_ua_kg.chr_8000098 Thalassiosira pseudonana CCMP1335 XP_002946253 Volvox carteri f. nagariensis XP_002947129 Volvox carteri f. nagariensis XP_002949576 Volvox carteri f. nagariensis XP_002949720 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR19375 0.0 4 650 No hit NA PRINTS PR00301 1.1E-87 8 21 IPR013126 Heat shock protein 70 family SUPERFAMILY SSF53067 1.1E-69 8 191 No hit NA Pfam PF00012 3.5E-276 9 618 IPR013126 Heat shock protein 70 family ProSitePatterns PS00297 NA 12 19 IPR018181 Heat shock protein 70, conserved site PRINTS PR00301 1.1E-87 36 48 IPR013126 Heat shock protein 70 family PRINTS PR00301 1.1E-87 58 66 IPR013126 Heat shock protein 70 family PRINTS PR00301 1.1E-87 146 166 IPR013126 Heat shock protein 70 family SUPERFAMILY SSF53067 7.4E-70 198 388 No hit NA ProSitePatterns PS00329 NA 203 216 IPR018181 Heat shock protein 70, conserved site PRINTS PR00301 1.1E-87 209 219 IPR013126 Heat shock protein 70 family PRINTS PR00301 1.1E-87 337 353 IPR013126 Heat shock protein 70 family ProSitePatterns PS01036 NA 340 354 IPR018181 Heat shock protein 70, conserved site PRINTS PR00301 1.1E-87 369 389 IPR013126 Heat shock protein 70 family SUPERFAMILY SSF100920 2.0E-65 392 549 No hit NA PRINTS PR00301 1.1E-87 396 415 IPR013126 Heat shock protein 70 family PRINTS PR00301 1.1E-87 477 493 IPR013126 Heat shock protein 70 family Coils Coil NA 518 542 No hit NA SUPERFAMILY SSF100934 6.4E-31 543 622 No hit NA
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787