Basic information
Locus name	AT3G62260
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Protein degradation/modification:protein kinase and phosphatases
Effect for Senescence	unclear
Gene Description	protein phosphatase 2C, putative / PP2C, putative phosphoprotein phosphatase (EC 3.1.3.16) 1A-alpha - Homo sapiens, PIR:S22423
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process protein dephosphorylation molecular function catalytic activity protein serine/threonine phosphatase activity
Sequence	AT3G62260.1 | Genomic | mRNA | CDS | Protein AT3G62260.2 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT3G62260.1  miRNA: ath-miR869 miRNA: ath-miR869 mfe: -24.8 kcal/mol  p-value: 0.035333  position:  1005  target 5' C  C   G       A      A 3'             UC ACU AUCUCGG ACCAGA              AG UGA UAGAGUU UGGUCU   miRNA  3' C  U           G        5'  target: AT3G62260.2  miRNA: ath-miR869 miRNA: ath-miR869 mfe: -24.8 kcal/mol  p-value: 0.035044  position:  994  target 5' C  C   G       A      A 3'             UC ACU AUCUCGG ACCAGA              AG UGA UAGAGUU UGGUCU   miRNA  3' C  U           G        5'
Ortholog Group
Ortholog Groups: OG5_149969	Accession Taxon NP_175238 Arabidopsis thaliana NP_188351 Arabidopsis thaliana NP_191785 Arabidopsis thaliana NP_850737 ( AT3G62260 ) Arabidopsis thaliana NP_001042801 Oryza sativa Japonica Group NP_001054565 Oryza sativa Japonica Group 29889.m003359 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR13832 1.5E-200 64 348 IPR015655 Protein phosphatase 2C SMART SM00332 4.2E-92 67 346 IPR001932 Protein phosphatase 2C (PP2C)-like SUPERFAMILY SSF81606 5.4E-76 71 348 IPR001932 Protein phosphatase 2C (PP2C)-like Pfam PF00481 7.2E-68 87 340 IPR001932 Protein phosphatase 2C (PP2C)-like SMART SM00331 0.0 92 348 IPR001932 Protein phosphatase 2C (PP2C)-like ProSitePatterns PS01032 NA 116 124 IPR000222 Protein phosphatase 2C, manganese/magnesium aspartate binding site