Basic information
Locus name	AT1G07430
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Protein degradation/modification:protein kinase and phosphatases
Effect for Senescence	unclear
Gene Description	protein phosphatase 2C, putative / PP2C, putative similar to GB:CAB90633 from [Fagus sylvatica]
Evidence	Genomic evidence:microarray data [Ref 1, Ref 2]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85 2: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process protein dephosphorylation molecular function catalytic activity protein serine/threonine phosphatase activity
Sequence	AT1G07430.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT1G07430.1  miRNA: ath-miR847 miRNA: ath-miR847 mfe: -27.6 kcal/mol  p-value: 0.011935  position:  296  target 5' G      C  C             U 3'             CGUCGA GA GGAGGAGGAG GA              GUAGUU CU UCUUCUCCUC CU   miRNA  3'                      A    5'
Ortholog Group
Ortholog Groups: OG5_160101	Accession Taxon NP_172223 ( AT1G07430 ) Arabidopsis thaliana NP_180499 Arabidopsis thaliana NP_187748 Arabidopsis thaliana NP_200730 Arabidopsis thaliana NP_001044788 Oryza sativa Japonica Group NP_001049674 Oryza sativa Japonica Group 30143.m001179 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description SUPERFAMILY SSF81606 5.5E-77 109 363 IPR001932 Protein phosphatase 2C (PP2C)-like SMART SM00332 7.0E-99 110 431 IPR001932 Protein phosphatase 2C (PP2C)-like PANTHER PTHR13832 3.3E-170 119 439 IPR015655 Protein phosphatase 2C Pfam PF00481 1.7E-69 121 361 IPR001932 Protein phosphatase 2C (PP2C)-like ProSitePatterns PS01032 NA 157 165 IPR000222 Protein phosphatase 2C, manganese/magnesium aspartate binding site SUPERFAMILY SSF81606 5.5E-77 406 434 IPR001932 Protein phosphatase 2C (PP2C)-like
Subcellular Localization
Localization	nucleus
Evidence	SUBAcon
Pubmed ID	23180787