Basic information
Locus name	AT3G17850
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Protein degradation/modification:protein kinase and phosphatases
Effect for Senescence	unclear
Gene Description	protein kinase, putative similar to IRE (incomplete root hair elongation) [Arabidopsis thaliana] gi|6729346|dbj|BAA89783; contains protein kinase domain Pfam:PF00069
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process protein phosphorylation molecular function ATP binding protein kinase activity protein serine/threonine kinase activity
Sequence	AT3G17850.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT3G17850.1  miRNA: ath-miR395a miRNA: ath-miR395a mfe: -28.9 kcal/mol  p-value: 0.026975  position:  1416  target 5' A   C            U C   A 3'             GAG UUCCCCCGGGCG C UCA              CUC AAGGGGGUUUGU G AGU   miRNA  3'                    A   C 5'  target: AT3G17850.1  miRNA: ath-miR395b miRNA: ath-miR395b mfe: -28.4 kcal/mol  p-value: 0.068330  position:  1416  target 5' A   C            U C   A 3'             GAG UUCCCCCGGGCG C UCA              CUC AGGGGGGUUUGU G AGU   miRNA  3'                    A   C 5'  target: AT3G17850.1  miRNA: ath-miR395c miRNA: ath-miR395c mfe: -28.4 kcal/mol  p-value: 0.067199  position:  1416  target 5' A   C            U C   A 3'             GAG UUCCCCCGGGCG C UCA              CUC AGGGGGGUUUGU G AGU   miRNA  3'                    A   C 5'  target: AT3G17850.1  miRNA: ath-miR395d miRNA: ath-miR395d mfe: -28.9 kcal/mol  p-value: 0.028706  position:  1416  target 5' A   C            U C   A 3'             GAG UUCCCCCGGGCG C UCA              CUC AAGGGGGUUUGU G AGU   miRNA  3'                    A   C 5'  target: AT3G17850.1  miRNA: ath-miR395e miRNA: ath-miR395e mfe: -28.9 kcal/mol  p-value: 0.028581  position:  1416  target 5' A   C            U C   A 3'             GAG UUCCCCCGGGCG C UCA              CUC AAGGGGGUUUGU G AGU   miRNA  3'                    A   C 5'  target: AT3G17850.1  miRNA: ath-miR395f miRNA: ath-miR395f mfe: -28.4 kcal/mol  p-value: 0.069077  position:  1416  target 5' A   C            U C   A 3'             GAG UUCCCCCGGGCG C UCA              CUC AGGGGGGUUUGU G AGU   miRNA  3'                    A   C 5'  target: AT3G17850.1  miRNA: ath-miR773 miRNA: ath-miR773 mfe: -28.7 kcal/mol  p-value: 0.016567  position:  748  target 5' A   A               C 3'             AGA AGAAGCUGGGAGUAG              UCU UUUUCGACCUUCGUU   miRNA  3' C   G               U 5'
Ortholog Group
Ortholog Groups: OG5_127530	Accession Taxon NP_001031155 Arabidopsis thaliana NP_001077679 Arabidopsis thaliana NP_001154409 Arabidopsis thaliana NP_175130 Arabidopsis thaliana NP_188412 ( AT3G17850 ) Arabidopsis thaliana NP_201037 Arabidopsis thaliana NP_564529 Arabidopsis thaliana 115025 Chlamydomonas reinhardtii ACO66366 Micromonas sp. RCC299 NP_001051060 Oryza sativa Japonica Group NP_001067302 Oryza sativa Japonica Group gw1.09.00.238.1 Ostreococcus tauri e_gw1.172.4.1 Physcomitrella patens subsp. patens e_gw1.285.1.1 Physcomitrella patens subsp. patens e_gw1.323.2.1 Physcomitrella patens subsp. patens e_gw1.353.1.1 Physcomitrella patens subsp. patens 27651.m000097 Ricinus communis 30147.m014197 Ricinus communis 30170.m014013 Ricinus communis XP_002946988 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description Coils Coil NA 317 338 No hit NA PANTHER PTHR24356 3.3E-193 874 1253 No hit NA SUPERFAMILY SSF56112 1.2E-90 879 1029 IPR011009 Protein kinase-like domain Pfam PF00069 1.4E-65 882 1171 IPR000719 Protein kinase, catalytic domain ProSiteProfiles PS50011 53.0 882 1171 IPR000719 Protein kinase, catalytic domain SMART SM00220 2.5E-103 882 1171 IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain ProSitePatterns PS00108 NA 1001 1013 IPR008271 Serine/threonine-protein kinase, active site Coils Coil NA 1049 1070 No hit NA SUPERFAMILY SSF56112 1.2E-90 1063 1214 IPR011009 Protein kinase-like domain ProSiteProfiles PS51285 9.5 1172 1277 IPR000961 AGC-kinase, C-terminal
Subcellular Localization
Localization	nucleus
Evidence	SUBAcon
Pubmed ID	23180787