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| Mutant name | LTS1 |
| Mutant/Transgenic |
mutant |
| Ecotype |
Rice (Oryza sativa) |
| Mutagenesis type |
T-DNA |
| (Semi-)Dominant/Recessive |
recessive |
| Description |
A point mutation in OsNaPRT1 leads to dwarfism and the withered leaf tip phenotype, and the lts1 mutant displays early leaf senescence compared to the wild type. Leaf tissue of lts1 exhibited significant DNA fragmentation and H2O2 accumulation, along with up-regulation of genes associated with senescence. The lts1 mutant also showed reduced expression of SIR2-like genes (OsSRT1 and OsSRT2) and increased acetylation of histone H3K9. deficiency in the NAD salvage pathway can trigger premature leafsenescence . |
| References |
1: Wu L, Ren D, Hu S, Li G, Dong G, Jiang L, Hu X, Ye W, Cui Y, Zhu L, Hu J, Zhang G, Gao Z, Zeng D, Qian Q, Guo L.Down-Regulation of a Nicotinate Phosphoribosyltransferase Gene, OsNaPRT1, Leads to Withered Leaf Tips.Plant Physiol. 2016 Jun;171(2):1085-98. doi: 10.1104/pp.15.01898. Epub 2016 Apr 5.
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| | Locus name |
LOC_Os03g62110 | | Alias |
OsNaPRT1 | | Organism |
Rice (Oryza sativa) | | Description |
encoding O. sativa nicotinate phosphoribosyltransferase (OsNaPRT1) in the NAD salvage pathway |
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