OTP72 - Plant Editosome Database - CNCB-NGDC

Summary

Editing Factor: OTP72
Synonym: ORGANELLE TRANSCRIPT PROCESSING 72
Description: Two mutants, otp71 and otp72, disrupted in genes encoding mitochondrial E-type PPR proteins with single editing defects in ccmFN 2 and rpl16 transcripts, respectively; E domains from the same organelle (chloroplast or mitochondria) were found to be exchangeable; however, swapping the E domain between organelles led to non-functional editing factors; E domains of mitochondrial and plastid PPR proteins are not functionally equivalent, and therefore that an important component of the putative editing complexes in the two organelles may be different
Protein Family: Pentatricopeptide repeat (PPR) protein
Subclass: E
Physical Interaction: NA
Construct Structure: PLS-E
Gene ID & Species: AT3G13880 (Arabidopsis thaliana)
Edited Gene(s): rpl16
Editing Type(s): C-to-U (3)
Publication(s): [1] The E domains of pentatricopeptide repeat proteins from different organelles are not functionally equivalent for RNA editing, Plant J, 2013. [doi:10.1111/tpj.12180]

Editing Details

Species Gene ID Organelle Edited Gene Position Region Nuclear Genome Organelle Genome Other Region Other Position Editing Type Codon Amino Acid Molecular Effect Experiment Details
Arabidopsis thaliana AT3G13880 Mitochondrion rpl16 NA CDS Arabidopsis Genome Initiative NC_001284.2 NA NA C-to-U CCA=>CUA P=>L Recoding
Experiment Details
Genotype (Ecotype) Allele Treatment Treatment Detail Mutant Type Phenotype Tissue Development Stage Detection Method Editing Frequency Editing Extent Mutant Effect PMID
Col-0WTControlControlNo mutantNormal growthLeaf15 daysPoisoned primer extension (PPE) assay100.00%CompleteNone23521509
SALK_040554otp72-1T-DNA insertionInsertion site in chromosome 34573006HomozygousNormal growthLeaf15 daysPoisoned primer extension (PPE) assay0.00%UneditedAbsent23521509
SAIL_080885otp72-2T-DNA insertionInsertion site in chromosome 34572523HomozygousSmaller than wild-type plantsLeaf15 daysPoisoned primer extension (PPE) assay0.00%UneditedAbsent23521509
Last update: Sep 2026 (version 2.0)