PGL3A - Plant Editosome Database - BIG Data Center

Summary

Editing Factor: PGL3A
Synonym: OsPGL3A
Description: OsPGL3A encodes a DYW-type pentatricopeptide repeat protein involved in chloroplast RNA processing and regulated chloroplast development
Protein Family: PPR
Subclass: DYW
Construct Structure: PLS-E1-E2-DYW
Gene ID & Species: Os03g0136700 (Oryza sativa)
Edited Gene(s): rps8    rpoC2
Editing Type(s): C-to-U (8)
Publication(s): [1] encodes a DYW-type pentatricopeptide repeat protein involved in chloroplast RNA processing and regulated chloroplast development., Molecular breeding : new strategies in plant improvement, 2024. [PMID=38549701]

Editing Details

Species Gene ID Organelle Edited Gene Position Region Editing Type Codon Amino Acid Molecular Effect Experiment Details
Oryza sativa Os03g0136700 Chloroplast rpoC2 4106 CDS C-to-U UCA=>UUA S=>L Recoding
Experiment Details
Genotype (Ecotype) Allele Treatment Treatment Detail Mutant Type Phenotype Tissue Development Stage Detection Method Editing Frequency Editing Extent Mutant Effect PMID
ZH11WTControlControlNo mutantNormalNANAReal-time fluorescent quantitative PCR; BioEdit80.00%HighNone38549701
NApgl3aNAA mutant library derived from Zhonghua 11 (ZH11); a japonica rice varietyNAPale green leaves and stunted growthNANAReal-time fluorescent quantitative PCR; BioEdit50.00%MediumDecreased38549701
NAcr-pgl3a-1A CRISPR-mediated mutantTwo targeted sequences within the exon region of OsPGL3A were designed; The target site sequences were cloned into a single guide RNA expression vector pYLgRNA and subsequently inserted into the targeHomozygous; KnockoutA pale green leaf phenotype with decreased chlorophyll contentNANAReal-time fluorescent quantitative PCR; BioEdit20.00%LowDecreased38549701
NAcr-pgl3a-2A CRISPR-mediated mutantTwo targeted sequences within the exon region of OsPGL3A were designed; The target site sequences were cloned into a single guide RNA expression vector pYLgRNA and subsequently inserted into the targeHomozygous; KnockoutA pale green leaf phenotype with decreased chlorophyll contentNANAReal-time fluorescent quantitative PCR; BioEdit30.00%LowSimilar38549701
Oryza sativa Os03g0136700 Chloroplast rps8 182 CDS C-to-U UCA=>UUA S=>L Recoding
Experiment Details
Genotype (Ecotype) Allele Treatment Treatment Detail Mutant Type Phenotype Tissue Development Stage Detection Method Editing Frequency Editing Extent Mutant Effect PMID
ZH11WTControlControlNo mutantNormalNANAReal-time fluorescent quantitative PCR; BioEdit90.00%HighNone38549701
NApgl3aNAA mutant library derived from Zhonghua 11 (ZH11); a japonica rice varietyNAPale green leaves and stunted growthNANAReal-time fluorescent quantitative PCR; BioEdit50.00%MediumDecreased38549701
NAcr-pgl3a-1A CRISPR-mediated mutantTwo targeted sequences within the exon region of OsPGL3A were designed; The target site sequences were cloned into a single guide RNA expression vector pYLgRNA and subsequently inserted into the targeHomozygous; KnockoutA pale green leaf phenotype with decreased chlorophyll contentNANAReal-time fluorescent quantitative PCR; BioEdit30.00%LowDecreased38549701
NAcr-pgl3a-2A CRISPR-mediated mutantTwo targeted sequences within the exon region of OsPGL3A were designed; The target site sequences were cloned into a single guide RNA expression vector pYLgRNA and subsequently inserted into the targeHomozygous; KnockoutA pale green leaf phenotype with decreased chlorophyll contentNANAReal-time fluorescent quantitative PCR; BioEdit40.00%MediumDecreased38549701
Last update: Jul 2021 (version 1.0)