SEL1 - Plant Editosome Database - CNCB-NGDC

Summary

Editing Factor: SEL1
Synonym: PDM1; SEEDLING LETHAL 1
Description: In sel1 mutants, plastid-encoded proteins involved in photosynthesis were rarely detected due to the lack of the corresponding transcripts; Furthermore, transcript profiles of plastid genes revealed that, in sel1 mutants, the transcript levels of plastid-encoded RNA polymerase-dependent genes were greatly reduced, but those of nuclear-encoded RNA polymerase-dependent genes were increased or not changed; Additionally, the RNA editing of two editing sites of the acetyl-CoA carboxylase beta subunit gene transcripts in the sel1 mutant was compromised, though it is not directly connected with the sel1 mutant phenotype
Protein Family: Pentatricopeptide repeat (PPR) protein
Subclass: PLS
Physical Interaction: NA
Construct Structure: PLS
Gene ID & Species: AT4G18520 (Arabidopsis thaliana)
Edited Gene(s): accD
Editing Type(s): C-to-U (4)
Publication(s): [1] Seedling Lethal1, a Pentatricopeptide Repeat Protein Lacking an E/E+ or DYW Domain in Arabidopsis, Is Involved in Plastid Gene Expression and Early Chloroplast Development, Plant Physiology, 2013. [doi:10.1104/pp.113.227199]

Editing Details

Species Gene ID Organelle Edited Gene Position Region Nuclear Genome Organelle Genome Other Region Other Position Editing Type Codon Amino Acid Molecular Effect Experiment Details
Arabidopsis thaliana AT4G18520 Chloroplast accD 794 CDS NA NA NA NA C-to-U UCG=>UUG S=>L Recoding
Experiment Details
Genotype (Ecotype) Allele Treatment Treatment Detail Mutant Type Phenotype Tissue Development Stage Detection Method Editing Frequency Editing Extent Mutant Effect PMID
Wassilewskija-2sel1T-DNA InsertionCollection of T-DNA insertion mutants in Arabidopsis (ecotype Wassilewskija-2 [Ws-2] background) and isolated several seedling-lethal mutants with pigment-defective phenotypesHomozygousExhibited a pigment-defective and seedling-lethal phenotypeSeedling7 daysDirect Sequencing of PCR Products16.00%PoorDecreased24144791
NAWTControlControlNo mutantNormalSeedling7 daysDirect Sequencing of PCR Products100.00%CompleteNone24144791
Arabidopsis thaliana AT4G18520 Chloroplast accD NA 3'UTR NA NA NA 1568 C-to-U NA=>NA NA=>NA NA
Experiment Details
Genotype (Ecotype) Allele Treatment Treatment Detail Mutant Type Phenotype Tissue Development Stage Detection Method Editing Frequency Editing Extent Mutant Effect PMID
Wassilewskija-2sel1T-DNA InsertionCollection of T-DNA insertion mutants in Arabidopsis (ecotype Wassilewskija-2 [Ws-2] background) and isolated several seedling-lethal mutants with pigment-defective phenotypesHomozygousExhibited a pigment-defective and seedling-lethal phenotypeSeedling7 daysDirect Sequencing of PCR Products0.00%UneditedAbsent24144791
NAWTControlControlNo mutantNormalSeedling7 daysDirect Sequencing of PCR Products91.00%HighNone24144791
Last update: Sep 2026 (version 2.0)