scTWAS Atlas
eQTL Dataset | PMID | Title | DOI | Tissue | Cell Type | Cell Condition | #eQTLs |
---|---|---|---|---|---|---|---|
Aquino et al. 2023 Nature | 37558883 | Dissecting human population variation in single-cell responses to SARS-CoV-2 | 10.1038/s41586-023-06422-9 | PBMC | B cell; CD4-positive T cell; CD8-positive T cell; Monocyte; Nature killer cell; Myeloid cell | SARS-CoV-2-stimulated; Influza stimulated; Normal | 18 |
Kang et al. 2017 Nat Biotechnol | 29227470 | Multiplexed droplet single-cell RNA-sequencing using natural genetic variation | 10.1038/nbt.4042 | PBMC | CD4-positive T cell; CD8-positive T cell; CD14-positive monocyte; FCGR3A-positive monocyte; Megakary | Normal | 83 |
Nathan et al. 2022 Nature | 35545678 | Single-cell eQTL models reveal dynamic T cell state dependence of disease loci | 10.1038/s41586-022-04713-1 | PBMC | Memory T cell; CD4-positive T cell; CD8-positive T cell | Normal | 9 |
Natri et al. 2024 Nat Genet | 38548990 | Cell type-specific and disease-associated eQTL in the human lung | 10.1038/s41588-024-01702-0 | Lung | Endothelial cell (alveolar capillary); Endothelial cell (arteriole); Endothelial cell (general capil | Normal | 11 |
Oelen et al. 2022 Nat Commun | 35672358 | Single-cell RNA-sequencing of peripheral blood mononuclear cells reveals widespread, context-specific gene expression regulation upon pathogenic exposure | 10.1038/s41467-022-30893-5 | PBMC | B cell; CD4-positive T cell; CD8-positive T cell; Monocyte; Nature killer cell; Megakaryocte | C. albicans-stimulated (24h); C. albicans-stimulated (3h); M.tuberculosis-stimulated (24h); M.tuberc | 234 |
Perez et al. 2022 Science | 35389781 | Single-cell RNA-seq reveals cell type-specific molecular and genetic associations to lupus | 10.1126/science.abf1970 | PBMC | B cell; CD4-positive T cell; CD8-positive T cell; Classical monocyte; Non-classical monocyte; Conven | Normal | 27 |
Randolph et al. 2021 Science | 34822289 | Genetic ancestry effects on the response to viral infection are pervasive but cell type-specific | 10.1126/science.abg0928 | PBMC | B cell; CD4-positive T cell; CD8-positive T cell; Monocyte; Nature killer cell | Influza stimulated; Normal | 4 |
Resztak et al. 2023 Genome Res | 37442575 | Genetic control of the dynamic transcriptional response to immune stimuli and glucocorticoids at single-cell resolution | 10.1101/gr.276765.122 | PBMC | B cell | Normal | 15 |
Schmiedel et al. 2022 Sci Immunol | 35213211 | Single-cell eQTL analysis of activated T cell subsets reveals activation and cell-type-dependent effects of disease-risk variants | 10.1126/sciimmunol.abm2508 | PBMC | CD4-positive T cell | Normal | 9 |
Wiljs et al. 2018 Nat Genet | 29610479 | Single-cell RNA sequencing identifies cell type-specific cis-eQTLs and co-expression QTLs | 10.1038/s41588-018-0089-9 | PBMC | B cell; CD4-positive T cell; CD8-positive T cell; Monocyte; Nature killer cell | Normal | 19 |