Trait

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Trait Label

GWAS Dataset Sample Size

>100,000

10,000 - 100,000

Strategy

Literature Curation

Data Analysis

Trait Distribution

Number of Associated Cell Types

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Trait Label	Trait Type	Associated Cell Types	#Assocaited Genes	GWAS Datasets
Alzheimer's Disease	Nervous System Diseases	B cell, CD14-positive monocyte, CD4-positive T cell, CD8-positive T cell, Classical monocyte, Conventional dendritic cell, Dendritic cell, Endothelial cell (alveolar capillary), Endothelial cell (lymphatic), Endothelial cell (systemic venous), Endothelial cell (venule), Megakaryocyte, Memory T cell, Monocyte, Myeloid cell, Nature killer cell, Non-classical monocyte, Plasmacytoid dendritic cell	124	GCST90027158; Thompson et al. 2022 Nat Commun
Anemia	Hemic and Lymphatic Diseases	B cell, CD14-positive monocyte, CD4-positive T cell, CD8-positive T cell, Classical monocyte, Conventional dendritic cell, Dendritic cell, Endothelial cell (alveolar capillary), Endothelial cell (arteriole), Endothelial cell (general capillary), Endothelial cell (lymphatic), Endothelial cell (systemic venous), Endothelial cell (venule), FCGR3A-positive monocyte, Megakaryocyte, Memory T cell, Monocyte, Myeloid cell, Nature killer cell	10610	GCST90077851
Arthritis	Musculoskeletal Diseases	B cell, CD4-positive T cell, CD8-positive T cell, Dendritic cell, Endothelial cell (lymphatic), Endothelial cell (systemic venous), Endothelial cell (venule), Megakaryocyte, Monocyte, Nature killer cell	52	GCST90080404
Asthma	Respiratory Tract Diseases	B cell, CD14-positive monocyte, CD4-positive T cell, CD8-positive T cell, Classical monocyte, Conventional dendritic cell, Dendritic cell, Endothelial cell (alveolar capillary), Endothelial cell (arteriole), Endothelial cell (general capillary), Endothelial cell (lymphatic), Endothelial cell (systemic venous), Endothelial cell (venule), FCGR3A-positive monocyte, Megakaryocyte, Memory T cell, Monocyte, Myeloid cell, Nature killer cell, Non-classical monocyte, Plasmacytoid dendritic cell	2591	GCST007799; Thompson et al. 2022 Nat Commun
Bipolar Disorder	Mental Disorders	B cell, CD4-positive T cell, CD8-positive T cell, Classical monocyte, Conventional dendritic cell, Nature killer cell, Non-classical monocyte, Plasmacytoid dendritic cell	50	Thompson et al. 2022 Nat Commun
Breast Cancer	Skin and Connective Tissue Diseases; Neoplasms	Epithelial cell, Stromal cell	11	Song et al. 2023 Nat Commun
Chronic Kidney Disease	Urogenital Diseases	B cell, CD4-positive T cell, CD8-positive T cell, Classical monocyte, Nature killer cell, Non-classical monocyte, Plasmacytoid dendritic cell	10	Thompson et al. 2022 Nat Commun
Coronary Artery Disease	Cardiovascular Diseases	B cell, CD4-positive T cell, CD8-positive T cell, Classical monocyte, Conventional dendritic cell, Nature killer cell, Plasmacytoid dendritic cell	13	Thompson et al. 2022 Nat Commun
COVID-19	Respiratory Tract Diseases	B cell, CD14-positive monocyte, CD4-positive T cell, CD8-positive T cell, Classical monocyte, Conventional dendritic cell, Dendritic cell, Endothelial cell (alveolar capillary), Endothelial cell (arteriole), Endothelial cell (general capillary), Endothelial cell (lymphatic), Endothelial cell (systemic venous), Endothelial cell (venule), FCGR3A-positive monocyte, Megakaryocyte, Memory T cell, Monocyte, Myeloid cell, Nature killer cell	8478	GCST011079
Crohn's Disease	Digestive System Diseases	B cell, CD4-positive T cell, CD8-positive T cell, Classical monocyte, Conventional dendritic cell, Nature killer cell, Non-classical monocyte, Plasmacytoid dendritic cell	123	Thompson et al. 2022 Nat Commun; Perez et al. 2022 Science

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