Cell type

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PMID	Title	DOI	Associated Traits	Associated Cell Type	Tissue	#TWAS Genes	eQTL Data Link	GWAS Link
35389781	Single-cell RNA-seq reveals cell type-specific molecular and genetic associations to lupus	10.1126/science.abf1970	Crohn's Disease; Rheumatoid Arthritis; Systemic Lupus Erythematosus	B cell; CD4-positive T cell; CD8-positive T cell; Nature killer cell; Conventional dendritic cell;	PBMC	8,888	https://doi.org/10.1038/s41467-019-11845-y	https://doi.org/10.1126/science.abf1970.
35609976	Biological insights into systemic lupus erythematosus through an immune cell-specific transcriptome-wide association study	10.1136/annrheumdis-2022-222345	Systemic Lupus Erythematosus	B cell; CD4-positive T cell; CD8-positive T cell; Nature killer cell; Monocyte	PBMC	132	https://doi.org/10.1038/ng.3885	https://doi.org/10.1136/annrheumdis-2020-219209
36171194	Multi-context genetic modeling of transcriptional regulation resolves novel disease loci	10.1038/s41467-022-33212-0	Alzheimer's Disease; Asthma; Bipolar Disorder; Chronic Kidney Disease; Coronary Artery Disease; Croh	B cell; CD4-positive T cell; CD8-positive T cell; Nature killer cell; Conventional dendritic cell;	PBMC	1,400	https://doi.org/10.1038/s41467-019-11845-y	https://doi.org/10.1038/s41467-022-33212-0
36690614	MiXcan: a framework for cell-type-aware transcriptome-wide association studies with an application to breast cancer	10.1038/s41467-023-35888-4	Breast Cancer	Epithelial cell; Stromal cell	Breast	11	https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000424.v8.p2 58,648	https://doi.org/10.1158/1055-9965.EPI-16-0106
38141910	A single-nucleus transcriptome-wide association study implicates novel genes in depression pathogenesis	10.1016/j.biopsych.2023.12.012	Depression	Astrocyte; Excitatory neuron; Inhibitory neuron; Microglial cell; Oligodendrocyte; Oligodendrocyte p	Brain	271	https://www.radc.rush.edu	https://doi.org/10.1038/s41593-018-0326-7

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