Trait

Trait Label:	Alzheimer's Disease
MeSH ID:	D000544
Ontology ID:	NCIT:C2866
MeSH Type:	Nervous System Diseases
Synonyms:	Alzheimer Syndrome; Alzheimer-Type Dementia (ATD); Alzheimer Type Dementia (ATD); Dementia, Alzheimer-Type (ATD); Alzheimer's Diseases; Alzheimer Diseases; Alzheimers Diseases; Alzheimer Dementia; Alzheimer Dementias; Dementia, Alzheimer; Alzheimer's Disease; Dementia, Senile; Senile Dementia; Dementia, Alzheimer Type; Alzheimer Type Dementia; Senile Dementia, Alzheimer Type; Alzheimer Type Senile Dementia; Primary Senile Degenerative Dementia; Alzheimer Sclerosis; Sclerosis, Alzheimer; Dementia, Primary Senile Degenerative; Dementia, Presenile; Presenile Dementia; Acute Confusional Senile Dementia; Senile Dementia, Acute Confusional; Alzheimer Disease, Early Onset; Early Onset Alzheimer Disease; Presenile Alzheimer Dementia; Alzheimer Disease, Late Onset; Late Onset Alzheimer Disease; Alzheimer's Disease, Focal Onset; Focal Onset Alzheimer's Disease; Familial Alzheimer Disease (FAD); Alzheimer Disease, Familial (FAD); Familial Alzheimer Diseases (FAD)
Description:	A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS.

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Trait	Cell Type	Cell Condition	Tissue	Strategy	Gene	Ensembl ID	Model	TWAS.Z	TWAS.P	TWAS.FDR	eQTL Dataset	GWAS Dataset