Accession |
PRJCA016013 |
Title |
Collagen 1-mediated CXCL1 secretion in tumor cells activates fibroblasts to promote radioresistance of esophageal cancer |
Relevance |
Medical |
Data types |
Transcriptome or Gene expression
Single cell sequencing
|
Organisms |
Mus musculus
|
Description |
Patient-derived xenografts (PDXs) are widely used models to elucidate the mechanisms of drug resistance because of their ability to preserve the tumor heterogeneity and therapeutic responsiveness of parental tumors. We isolated fresh tumor tissue from 6 PDX mice and performed scRNA-seq. |
Sample scope |
Monoisolate |
Release date |
2023-04-09 |
Publication |
PubMed ID |
Article title |
Journal name |
DOI |
Year |
37851572
|
Collagen 1-mediated CXCL1 secretion in tumor cells activates fibroblasts to promote radioresistance of esophageal cancer
|
Cell Reports
|
10.1016/j.celrep.2023.113270
|
2023
|
|
Grants |
Agency |
program |
Grant ID |
Grant title |
National Natural Science Foundation of China (NSFC)
|
|
81988101
|
|
National Natural Science Foundation of China (NSFC)
|
National Science Funds for Distinguished Young Scholars
|
81725015
|
|
Beijing Outstanding Young Scientist Program
|
|
BJJWZYJH01201910023027
|
|
Chinese Academy Medical Sciences Innovation Fund for Medical Sciences
|
|
2021-I2M-1-013
|
|
National Natural Science Foundation of China (NSFC)
|
|
82203256
|
|
|
Submitter |
XINJIE
CHEN (imchenxj@163.com)
|
Organization |
CAMS Cancer Hospital |
Submission date |
2023-04-03 |