Accession PRJCA016013
Title Collagen 1-mediated CXCL1 secretion in tumor cells activates fibroblasts to promote radioresistance of esophageal cancer
Relevance Medical
Data types Transcriptome or Gene expression
Single cell sequencing
Organisms Mus musculus
Description Patient-derived xenografts (PDXs) are widely used models to elucidate the mechanisms of drug resistance because of their ability to preserve the tumor heterogeneity and therapeutic responsiveness of parental tumors. We isolated fresh tumor tissue from 6 PDX mice and performed scRNA-seq.
Sample scope Monoisolate
Release date 2023-04-09
Publication
PubMed ID Article title Journal name DOI Year
37851572 Collagen 1-mediated CXCL1 secretion in tumor cells activates fibroblasts to promote radioresistance of esophageal cancer Cell Reports 10.1016/j.celrep.2023.113270 2023
Grants
Agency program Grant ID Grant title
National Natural Science Foundation of China (NSFC) 81988101
National Natural Science Foundation of China (NSFC) National Science Funds for Distinguished Young Scholars 81725015
Beijing Outstanding Young Scientist Program BJJWZYJH01201910023027
Chinese Academy Medical Sciences Innovation Fund for Medical Sciences 2021-I2M-1-013
National Natural Science Foundation of China (NSFC) 82203256
Submitter XINJIE CHEN (imchenxj@163.com)
Organization CAMS Cancer Hospital
Submission date 2023-04-03

Project Data

Resource name Description
BioSample (6)  show -
GSA (1) -
CRA010501 Collagen 1-mediated CXCL1 secretion in tumor cells activates fibroblasts to promote radioresistance of esophageal cancer