e.g., HRA000087; HRA000150
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HRA006117
   HRA006117.xlsx
Title:
Aging and comprehensive molecular profiling in acute myeloid leukemia
Release date:
2024-02-15
Description:
Acute myeloid leukemia (AML) is an aging-related and heterogeneous hematopoietic malignancy. To date, the molecular basis and its clinical significance of aging including common genomic and transcriptomic alterations in AML has not been fully elucidated. In this study, a total of 1,348 newly diagnosed AML patients from three centers were enrolled and subjected to RNA sequencing (RNA-Seq, n=1,348) and targeted or whole exome sequencing (TES/WES, n=1,286). The correlation of age-related factors including gene fusions, genetic mutations, and gene expression networks or pathways between age/gender/clonal hematopoiesis (CH) groups were systematically analyzed.
Data Accessibility:   
Controlled access Request Data
BioProject:
PRJCA020863
Study type:
Disease Study
Disease name:
acute myeloid leukemia
Data Access Committee

For each controlled access study, there is a corresponding Data Access Committee(DAC) to determine the access permissions. Access to actual data files is not managed by NGDC.


DAC NO.:
HDAC001538
DAC name:
Shanghai Institute of Hematology
Contact person:
Shen Yang
Email:
shen_yang@126.com
Description:
Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China
Individuals & samples
Individual Accession
Individual Name
Gender
Sample Accession
Sample Name
Sample Description
Individual Accession
Individual Name
Gender
Sample Accession
Sample Name
Sample Description
HRI768691SIH509maleHRS1008013SIH509Primary AML
HRI768692SIH511maleHRS1008014SIH511Primary AML
HRI768693SIH513femaleHRS1008015SIH513Primary AML
HRI768694SIH514maleHRS1008016SIH514Primary AML
HRI768695SIH519maleHRS1008017SIH519Primary AML
HRI768696SIH527femaleHRS1008018SIH527Primary AML
HRI768697SIH530maleHRS1008019SIH530Primary AML
HRI768698SIH531maleHRS1008020SIH531Primary AML
HRI768699SIH532maleHRS1008021SIH532Primary AML
HRI768700SIH533maleHRS1008022SIH533Primary AML
Showing 1 to 10 of 835 rows rows per page
Files
Request Data
Run accession
Files
Experiment
Experiment title
Platform
Sample
Run accession
Files
Experiment
Experiment title
Platform
Sample
HRR1464788HRR1464788_f1.fq.gz (4.35 GB)HRX1142051mRNA_AML_SIH509Illumina NovaSeq 6000HRS1008013 (SAMC3236753)
HRR1464788HRR1464788_r2.fq.gz (4.54 GB)HRX1142051mRNA_AML_SIH509Illumina NovaSeq 6000HRS1008013 (SAMC3236753)
HRR1464789HRR1464789_f1.fq.gz (3.35 GB)HRX1142052mRNA_AML_SIH511Illumina NovaSeq 6000HRS1008014 (SAMC3236754)
HRR1464789HRR1464789_r2.fq.gz (3.44 GB)HRX1142052mRNA_AML_SIH511Illumina NovaSeq 6000HRS1008014 (SAMC3236754)
HRR1464790HRR1464790_f1.fq.gz (3.63 GB)HRX1142053mRNA_AML_SIH513Illumina NovaSeq 6000HRS1008015 (SAMC3236755)
HRR1464790HRR1464790_r2.fq.gz (3.75 GB)HRX1142053mRNA_AML_SIH513Illumina NovaSeq 6000HRS1008015 (SAMC3236755)
HRR1464791HRR1464791_f1.fq.gz (4.31 GB)HRX1142054mRNA_AML_SIH514Illumina NovaSeq 6000HRS1008016 (SAMC3236756)
HRR1464791HRR1464791_r2.fq.gz (4.31 GB)HRX1142054mRNA_AML_SIH514Illumina NovaSeq 6000HRS1008016 (SAMC3236756)
HRR1464792HRR1464792_f1.fq.gz (5.58 GB)HRX1142055mRNA_AML_SIH519Illumina NovaSeq 6000HRS1008017 (SAMC3236757)
HRR1464792HRR1464792_r2.fq.gz (5.88 GB)HRX1142055mRNA_AML_SIH519Illumina NovaSeq 6000HRS1008017 (SAMC3236757)
Showing 1 to 10 of 1670 rows rows per page
Submitter:   Shen Yang / shen_yang@126.com
Organization:   Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Submission date:   2023-10-29
Requests:   1