The detail information of Lissencephaly
Basic Information

Disease Description: An abnormal brain development where the surface lacks gyri (the grooves).

Inherit Mode: unknown.

Disease Symptom: The signs that are seen with this rare condition become evident shortly after birth. There are behavioural abnormalities (which can be severe), and the pups develop seizures and are blind.

Disease Cause: -

Disease Diagnose: Your veterinarian may suspect this condition based on the clinical signs and absence of abnormalities on routine diagnostic tests. The diagnosis can be confirmed by MRI (magnetic resonance imaging) or on post-mortem.

Treat Method: There is no treatment.

Breeder Advice: Affected animals should not be bred. Although little is known about the inheritance of this rare but devastating condition, it is best to avoid breeding parents or siblings of affected pups.

Disease Description Source: Link

Associated Diseases
There are no associated diseases in OMIA/CIDD.
Associated Breeds
iDog Breed Number Breed Name Personality Height Weight Breed Source
CB131 Irish Setter Outgoing, sweet-natured, active, and trainable 68.6 cm (male), 63.5 cm (female) 31.8 kg (male), 27.2 kg (female) Ireland
CB153 Lhasa Apso(Long-Haired Lhasa Dog) Smart, confident, complex; a family comedian, but regally aloof with strangers 25.4-27.9 cm (male), slightly smaller (female) 5.4-8.2 kg Tibet
CB154 Lowchen(Little Lion Dog) Affectionate, Outgoing, Positive 12-14 inches 15 pounds Germany, France, Netherlands, Spain
CB257 Wire-Haired Fox Terrier Alert, quick of movement, keen of expression, on tiptoe of expectation at slightest provocation. Friendly, forthcoming and fearless. 39 cm 8.25 kg United Kingdom (England)
References
1995 Fenner, W.R. :
Diseases of the brain W.B. Saunders Co., Toronto. S.J. Ettinger and E.C. Feldman (eds.) Textbook of Veterinary Internal Medicine, pp. 578-629