Objective: To determine the pooled estimate of risky sexual behaviour among university students in sub Saharan Africa. Methods: A meta analytic study conducted to identify predictors of risky sexual behavior among university students. Databases from PubMed, African Journals Online, Science Direct, Google Scholar were used to identify appropriate studies. The combined effect estimates for each outcome were computed in Meta XL using random effects. Results: The estimated pooled prevalence of sexual activity among university students was 51.0% (95% CI: 43.0% - 59.0%). Pooled prevalence for multiple sexual partners was 36.0% (95% CI: 30.0% - 42.0%), inconsistent condom use, 53.0% (95% CI: 46% - 61.0%) and for at least one risky sexual behavior, 65.0% (48.0% - 81.0%). Males were 3.36 times [OR: 3.05; 95% CI: 2.59 - 4.37] more likely to have multiple sexual partners than females. This review also indicated that males were 2.99 times [OR: 2.99; 95% CI: 1.40 - 6.40] more likely to engage in at least one risky sexual behavior than females. Conclusion: Inconsistent condom use and multiple sexual partners were the most rampant risky sexual behaviors in Universities in Sub-Saharan Africa. Sustained risk communication on Sexual and Reproductive Health and youth friendly programs are highly recommended.
