Hyperimmune serum with the high content of antibodies to the saliva of noninfected ticks when injected into vertebrates, induced the development of resistance preventing the ticks from sticking to the skin and satiation, thus reducing the number of blood-sucking ticks reaching satiation and decreasing the weight of satiated ticks; as a result, the productivity of female ticks decreased the the number of ticks sharply dropped. When ticks infected with tick-borne encephalitis virus parasitized on the animals immune against the saliva antigens of noninfected ticks, the virus titers in the blood of these animals were lower than in the controls, and no infection of ticks, formerly free of the virus, occurred.
