- J R Jørgensen: Medicinsk afdeling B, Hillerød Sygehus.
The intestinal epithelium has the dual functions of being an absorptive organ and acting as a barrier to the permeation of potentially harmful compounds and organisms. The theory behind measurement of intestinal permeability in human studies as well as selected studies of intestinal permeability are presented. Intestinal permeability studies as diagnostic, prognostic, sequential and screening parameters are illuminated- and the importance of changed intestinal permeability in the pathogenesis and maintenance of disease is discussed. Measuring of intestinal permeability can be used as both a prognostic and diagnostic tool, and maybe also as a screening parameter. The method may in the future turn out to be an important tool in the management of various diseases.