- Z T Zhou: Department of Oral Medicine, Ninth People's Hospital, School of Stomatology,Shanghai Second Medical Unviersity.Shanghai 200011,China.
Premalignant model was established successfully in this study.At the same time,we applied compound Gynostemma Pentaphyllum Mak to conduct experimental research to block development of oral mucosal premalignancy.The results showed from uniform to granular or verrucous leukoplakia,there was the stage in which Gynostemma Pentaphyllum Mak could block oral mucosal premalignancies.The group which was firstly given to Gynostemma Pentaphllum Mak then smeared was more advantageous than the one which firstly smeared then given to the same drug.The experimentation demonstrated that Gynostemma Pentaphyllum had the functions of preventing and resisting cancer.There will be applied prospect in preventing and treating oral mucosal premalignancy.We should make further research in the future.