Personality disorders evident by early adulthood and risk for anxiety disorders during middle adulthood.

Jeffrey G Johnson, Patricia Cohen, Stephanie Kasen, Judith S Brook
Author Information
  1. Jeffrey G Johnson: Columbia University and the New York State Psychiatric Institute, Box 47, 1051 Riverside Drive, New York, NY 10032, USA. jjohnso@pi.cpmc.columbia.edu

Abstract

Data from the Children in the Community Study, a prospective longitudinal investigation, were used to investigate the association of personality disorder (PD) traits, evident by early adulthood, with risk for development of anxiety disorders by middle adulthood. Individuals without a history of anxiety disorders who met diagnostic criteria for >or=1 PD by early adulthood were at markedly elevated risk for agoraphobia, generalized anxiety disorder, obsessive-compulsive disorder, and panic disorder by middle adulthood. Antisocial, avoidant, borderline, dependent, depressive, histrionic, obsessive-compulsive, passive-aggressive, and schizotypal PD traits, evident by early adulthood, were associated with elevated risk for >or=1 anxiety disorder during middle adulthood. These associations remained significant after a history of anxiety disorder and co-occurring Axis I psychiatric disorder was controlled statistically. Findings of this study suggest that some types of PD traits that become evident by early adulthood may contribute to increased risk for the development of anxiety disorders by middle adulthood.

Grants

  1. DA-03188/NIDA NIH HHS
  2. MH-36971/NIMH NIH HHS
  3. MH-49191/NIMH NIH HHS
  4. MH-60911/NIMH NIH HHS

MeSH Term

Adolescent
Adult
Age of Onset
Anxiety Disorders
Female
Humans
Logistic Models
Male
Personality Disorders
Prospective Studies
Risk
United States

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