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Nucleic acids research
Jul, 2007;35 (Web Server issue): W121-5.

FGF: a web tool for Fishing Gene Family in a whole genome database.

Hongkun Zheng, Junjie Shi, Xiaodong Fang, Yuan Li, S��ren Vang, Wei Fan, Junyi Wang, Zhang Zhang, Wen Wang, Karsten Kristiansen, Jun Wang
Author Information
  1. Hongkun Zheng: Beijing Institute of Genomics of Chinese Academy of Sciences, Beijing Genomics Institute, Beijing 101300, China.
PMID: 17584790 DOI: 10.1093/nar/gkm426

Abstract

Gene duplication is an important process in evolution. The availability of genome sequences of a number of organisms has made it possible to conduct comprehensive searches for duplicated genes enabling informative studies of their evolution. We have established the FGF (Fishing Gene Family) program to efficiently search for and identify gene families. The FGF output displays the results as visual phylogenetic trees including information on gene structure, chromosome position, duplication fate and selective pressure. It is particularly useful to identify pseudogenes and detect changes in gene structure. FGF is freely available on a web server at http://fgf.genomics.org.cn/

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Grants

  1. /Wellcome Trust

MeSH Term

Algorithms
Animals
Chromosome Mapping
Chromosomes
Computational Biology
Evolution, Molecular
Gene Duplication
Genome
Humans
Information Storage and Retrieval
Internet
Models, Genetic
Phylogeny
Software
User-Computer Interface
Journal Article Research Support, Non-U.S. Gov't

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