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Psychosomatics
2009 Mar-Apr;50 (2): 138-46.

Uncertainty, symptoms, and quality of life in persons with chronic hepatitis C.

Donald E Bailey, Lawrence Landerman, Julie Barroso, Patricia Bixby, Merle H Mishel, Andrew J Muir, Lisa Strickland, Elizabeth Clipp
Author Information
  1. Donald E Bailey: Duke University School of Nursing, DUMC PO Box 3322, Durham, NC 27710, USA. chip.bailey@duke.edu
PMID: 19377022 DOI: 10.1176/appi.psy.50.2.138

Abstract

BACKGROUND: Chronic hepatitis C (CHC) is the most common blood-borne infection in the United States, but little is known about illness uncertainty in these patients.
OBJECTIVE: The authors examined the constructs of illness uncertainty.
METHOD: In this cross-sectional study, Mishel's Uncertainty in Illness Scale was used to examine these constructs (ambiguity, complexity, inconsistency, unpredictability) and their relationships with fatigue, pain, depressive symptoms, comorbidity, and quality of life (QOL) in 126 CHC patients undergoing a watchful-waiting protocol.
RESULTS: The Ambiguity subscale had the strongest relationships with depressive symptoms, QOL, and fatigue, and three of the four subscales were significantly correlated with pain.
CONCLUSION: The results suggest targets for patient self-management interventions.

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Grants

  1. P20 NR007795/NINR NIH HHS
  2. R15 NR008704/NINR NIH HHS
  3. 1 R15 NR 008794-01A1/NINR NIH HHS
  4. 1P20NR07795-01/NINR NIH HHS

MeSH Term

Adult
Aged
Depression
Fatigue
Female
Hepatitis C, Chronic
Humans
Male
Middle Aged
Pain
Prevalence
Quality of Life
Severity of Illness Index
Young Adult
Journal Article Research Support, N.I.H., Extramural
Article has an altmetric score of 3

Word Cloud

Created with Highcharts 10.0.0symptomshepatitisCCHCillnessuncertaintypatientsconstructsUncertaintyrelationshipsfatiguepaindepressivequalitylifeQOLBACKGROUND:Chroniccommonblood-borneinfectionUnitedStateslittleknownOBJECTIVE:authorsexaminedMETHOD:cross-sectionalstudyMishel'sIllnessScaleusedexamineambiguitycomplexityinconsistencyunpredictabilitycomorbidity126undergoingwatchful-waitingprotocolRESULTS:AmbiguitysubscalestrongestthreefoursubscalessignificantlycorrelatedCONCLUSION:resultssuggesttargetspatientself-managementinterventionspersonschronic

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