[Study of antibiotic resistance of enterococci strains received in 2009 in the National Reference Centre for Enterococci].

Mihaela-Cristin Giucă, Anca Petrini, Tuca Ceornea, Vasilica Ungureanu
Author Information
  1. Mihaela-Cristin Giucă: INCDMI Cantacuzino.

Abstract

Enterococci are a frequent cause of a variety of human infections, the most common being urinary tract infection followed by bacteraemia, meningitis and endocarditis from hospitalized patients.
OBJECTIVE: The study and monitoring of antibiotic resistance of enterococci strains isolated and confirmed in 2009.
MATERIALS AND METHODS: Identification of 30 strains received in 2009 was based on phenotypic characteristics (microscopy, culture and biochemical characters); antibiotic susceptibility testing was performed according to CLSI standards 2009 by diffusion test and MIC by agar dilution and E-test.
RESULT: The strains belonged to the following species: E. faecalis (18), E. faecium (6), E. gallinarum (5), and E. durans (1), and were isolated from: blood cultures, urine, pus-wound, cerebrospinal fluid (CSF) and catheter. Antibiotic susceptibility testing showed susceptibility to different antibiotics depending on the species and also on the type of clinical samples.
CONCLUSIONS: Due to the small number of strains, no resistance phenotypes could be determined. As emergence of antibiotic resistant enterococci is well known, continuous surveillance of antibiotic susceptibility and molecular study of this issue are required.

MeSH Term

Academies and Institutes
Anti-Bacterial Agents
Drug Resistance, Bacterial
Enterococcus
Gram-Positive Bacterial Infections
Humans
Microbial Sensitivity Tests
Romania
Urinary Tract Infections

Chemicals

Anti-Bacterial Agents

Word Cloud

Created with Highcharts 10.0.0antibioticstrains2009susceptibilityEresistanceenterococcistudyisolatedreceivedtestingEnterococcifrequentcausevarietyhumaninfectionscommonurinarytractinfectionfollowedbacteraemiameningitisendocarditishospitalizedpatientsOBJECTIVE:monitoringconfirmedMATERIALSANDMETHODS:Identification30basedphenotypiccharacteristicsmicroscopyculturebiochemicalcharactersperformedaccordingCLSIstandardsdiffusiontestMICagardilutionE-testRESULT:belongedfollowingspecies:faecalis18faecium6gallinarum5durans1from:bloodculturesurinepus-woundcerebrospinalfluidCSFcatheterAntibioticshoweddifferentantibioticsdependingspeciesalsotypeclinicalsamplesCONCLUSIONS:Duesmallnumberphenotypesdeterminedemergenceresistantwellknowncontinuoussurveillancemolecularissuerequired[StudyNationalReferenceCentreEnterococci]

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