- S Kandemir: Abteilung für Orale Diagnose und Radiologie (Prof Dr. G. Lomçalı;), Zahnmedizinische Fakultät, Ege Universität, Bornova Izmir, Türkei.
First lesions of Cowden syndrome appear in the oral cavity and on the skin. Malignant transformation is a late, common event in thyroid and breast. The early diagnosis of Cowden disease prior to the development of internal malignancy, particularly of the breast and the thyroid gland, is very important. We emphasize that the dentist may be the first health care professional who recognizes the syndrome, and this is a crucial step in the prevention and cure of the predictable malignancy. This article presents a typical case of Cowden disease.