[Cowden syndrome].

O Ennibi, M Guedira, N Amrani
Author Information
  1. O Ennibi: Service de parodontologie, faculté de médecine dentaire, université Mohammed V Souissi, Rabat, Morocco. o.ennibi@um5s.net.ma

Abstract

INTRODUCTION: Cowden syndrome is rare; oral symptoms are not always diagnosed. This case of Cowden syndrome was revealed by gingival hypertrophy.
OBSERVATION: A 21-year-old female patient consulted for gingival hypertrophy and multiple papules in the mouth. She had a history of thyroid lobectomy due to a goiter. The gingival papillomatosis and the goiter suggested a Cowden syndrome. The diagnosis was confirmed clinically by facial skin papules.
DISCUSSION: Cutaneous and oral lesions are usually the first symptoms of the syndrome. Diffuse gingival papillomatosis may suggest a Cowden syndrome and should lead to screen for associated symptoms. A high-risk diagnosis of breast and thyroid cancer is associated to Cowden syndrome and the patient should have a yearly follow-up.

MeSH Term

Cecum
Female
Gingival Hypertrophy
Hamartoma Syndrome, Multiple
Humans
Intestinal Polyps
Young Adult

Word Cloud

Created with Highcharts 10.0.0syndromeCowdengingivalsymptomsoralhypertrophypatientpapulesthyroidgoiterpapillomatosisdiagnosisassociatedINTRODUCTION:rarealwaysdiagnosedcaserevealedOBSERVATION:21-year-oldfemaleconsultedmultiplemouthhistorylobectomyduesuggestedconfirmedclinicallyfacialskinDISCUSSION:CutaneouslesionsusuallyfirstDiffusemaysuggestleadscreenhigh-riskbreastcanceryearlyfollow-up[Cowdensyndrome]

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