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Oncoimmunology
Dec 01, 2013;2 (12): e26622.

KIR/HLA immunogenetic background influences the evolution of hepatocellular carcinoma.

Elisabetta Cariani, Gabriele Missale
Author Information
  1. Elisabetta Cariani: Clinical Pathology-Toxicology; Ospedale S Agostino-Estense; Modena, Italy.
  2. Gabriele Missale: U.O. Infectious Diseases and Hepatology; Azienda Ospedaliero-Universitaria di Parma; Parma, Italy.
PMID: 24501686 DOI: 10.4161/onci.26622

Abstract

Natural killer (NK) cells play a major role in antitumor immune responses. Recent results from our laboratory demonstrate the impact of the immunogenetic background on the activity of NK cells and hence on the outcome of hepatocellular carcinoma, disclosing perspectives for the development of NK-cell based therapies.

Keywords

CD56 HCC HLA immunotherapy killer cell Ig-like receptor natural killer cell

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Journal Article

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