OpenLB
Open Library of Bioscience
Advanced Search
Current radiology reports
2014;2 41.

Sodium MR Imaging of Articular Cartilage Pathologies.

Stefan Zbýň, Vladimír Mlynárik, Vladimir Juras, Pavol Szomolanyi, Siegfried Trattnig
Author Information
  1. Stefan Zbýň: High Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.
  2. Vladimír Mlynárik: High Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.
  3. Vladimir Juras: High Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.
  4. Pavol Szomolanyi: High Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.
  5. Siegfried Trattnig: High Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.
PMID: 24683524 DOI: 10.1007/s40134-014-0041-4

Abstract

Many studies have proved that noninvasive sodium MR imaging can directly determine the cartilage GAG content, which plays a central role in cartilage homeostasis. New technical developments in the recent decade have helped to transfer this method from in vitro to pre-clinical in vivo studies. Sodium imaging has already been applied for the evaluation of cartilage and repair tissue in patients after various cartilage repair surgery techniques and in patients with osteoarthritis. These studies showed that this technique could be helpful not only for assessment of the cartilage status, but also predictive for osteoarthritis. However, due to the low detectable sodium MR signal in cartilage, sodium imaging is still challenging, and further hardware and software improvements are necessary for translating sodium MR imaging into clinical practice, preferably to 3T MR systems.

Keywords

Cartilage Osteoarthritis Repair tissue Sodium MR imaging

References

  1. J Magn Reson Imaging. 2007 Feb;25(2):262-9 [PMID: 17260399]
  2. Magn Reson Med. 1997 Dec;38(6):863-7 [PMID: 9402184]
  3. J Rheumatol. 1991 Mar;18(3):428-35 [PMID: 1856811]
  4. NMR Biomed. 2006 Nov;19(7):781-821 [PMID: 17075961]
  5. NMR Biomed. 2012 Apr;25(4):530-7 [PMID: 21853493]
  6. Eur J Radiol. 2006 Jan;57(1):16-23 [PMID: 16203119]
  7. Arthritis. 2011;2011:475684 [PMID: 22046518]
  8. N Engl J Med. 1994 Oct 6;331(14):889-95 [PMID: 8078550]
  9. Magn Reson Med. 2008 Jul;60(1):135-45 [PMID: 18581326]
  10. Arthritis Res Ther. 2003;5(1):R60-73 [PMID: 12716454]
  11. Eur Radiol. 2014 Feb;24(2):494-501 [PMID: 24081646]
  12. Clin Orthop Relat Res. 1994 May;(302):259-65 [PMID: 8168311]
  13. Magn Reson Med. 2007 Dec;58(6):1182-95 [PMID: 17969013]
  14. J Magn Reson Imaging. 2009 Sep;30(3):606-14 [PMID: 19711406]
  15. J Orthop Res. 1992 Jan;10(1):1-13 [PMID: 1309384]
  16. Biochim Biophys Acta. 1969 May 6;177(3):492-500 [PMID: 4239606]
  17. Br J Rheumatol. 1991 Aug;30(4):318 [PMID: 1863838]
  18. Connect Tissue Res. 1989;19(2-4):149-76 [PMID: 2805680]
  19. J Magn Reson. 1999 Dec;141(2):286-90 [PMID: 10579951]
  20. J Bone Joint Surg Am. 2003;85-A Suppl 2:8-16 [PMID: 12721340]
  21. Magn Reson Med. 2009 Aug;62(2):532-7 [PMID: 19353662]
  22. Magn Reson Med. 2012 Dec;68(6):1807-14 [PMID: 22377960]
  23. IEEE Trans Med Imaging. 2000 Apr;19(4):306-17 [PMID: 10909926]
  24. Magn Reson Med. 2009 Dec;62(6):1565-73 [PMID: 19859915]
  25. Invest Radiol. 2000 Oct;35(10):622-38 [PMID: 11041156]
  26. Magn Reson Med. 1997 Dec;38(6):1022-8 [PMID: 9402205]
  27. J Magn Reson Imaging. 2010 Aug;32(2):446-51 [PMID: 20677276]
  28. Radiology. 2011 Jul;260(1):257-64 [PMID: 21460030]
  29. Osteoarthritis Cartilage. 2000 Jul;8(4):288-93 [PMID: 10903883]
  30. Magn Reson Med. 2007 Jan;57(1):74-81 [PMID: 17191248]
  31. J Bone Joint Surg Am. 2011 Mar 16;93(6):533-9 [PMID: 21411703]
  32. Eur Radiol. 2012 Jun;22(6):1341-9 [PMID: 22350437]
  33. J Magn Reson. 2012 Jan;214(1):360-5 [PMID: 22204825]
  34. J Neurol. 2012 Nov;259(11):2385-92 [PMID: 22544297]
  35. Radiology. 2013 Aug;268(2):481-91 [PMID: 23468572]
  36. Magn Reson Med. 2006 Mar;55(3):575-82 [PMID: 16450366]
  37. Radiology. 2004 Jun;231(3):900-5 [PMID: 15163825]
  38. Arthritis Res Ther. 2009;11(3):R92 [PMID: 19545413]
  39. Osteoarthritis Cartilage. 2012 Jan;20(1):13-21 [PMID: 22044841]
  40. Magn Reson Med. 1999 Dec;42(6):1146-54 [PMID: 10571937]
  41. Invest Radiol. 2011 Sep;46(9):539-47 [PMID: 21577129]
  42. Magn Reson Med. 2012 Sep;68(3):841-9 [PMID: 22180051]
  43. Magn Reson Med. 1997 May;37(5):706-15 [PMID: 9126944]
  44. J Biol Chem. 2004 Feb 20;279(8):6286-95 [PMID: 14660626]
  45. Arthritis Rheum. 1999 May;42(5):993-1002 [PMID: 10323456]
  46. IEEE Trans Med Imaging. 1995;14(3):596-607 [PMID: 18215864]
  47. Arthroscopy. 1993;9(3):318-21 [PMID: 8323618]
  48. J Orthop Res. 2005 Sep;23(5):1128-38 [PMID: 15936918]
  49. Biomaterials. 1992;13(2):67-97 [PMID: 1550898]
  50. Int J Exp Pathol. 2009 Dec;90(6):575-86 [PMID: 19958398]
  51. Radiology. 2010 Oct;257(1):175-84 [PMID: 20713608]
  52. Radiology. 2012 Jan;262(1):199-205 [PMID: 22056685]
  53. J Magn Reson Imaging. 1993 Jul-Aug;3(4):565-8 [PMID: 8347947]
  54. Magn Reson Med. 1995 Jan;33(1):82-7 [PMID: 7891540]
  55. Acad Radiol. 2004 Jan;11(1):21-8 [PMID: 14746398]
  56. J Bone Joint Surg Am. 2003 Feb;85(2):185-92 [PMID: 12571292]
  57. Arthritis Rheum. 2008 Jan;58(1):26-35 [PMID: 18163497]
  58. Magn Reson Med. 2013 Nov;70(5):1434-9 [PMID: 23233430]
  59. Magn Reson Med. 2011 Nov;66(5):1303-11 [PMID: 21469190]
  60. Lancet. 2011 Jun 18;377(9783):2115-26 [PMID: 21684382]
  61. Matrix Biol. 2004 Oct;23(6):381-91 [PMID: 15533759]
  62. Magn Reson Med. 1999 Jan;41(1):30-4 [PMID: 10025608]
  63. Ann Rheum Dis. 2013 May;72(5):707-14 [PMID: 22730370]
  64. Magn Reson Med. 2002 Feb;47(2):284-91 [PMID: 11810671]
  65. Magn Reson Med. 1998 May;39(5):697-701 [PMID: 9581599]
  66. Clin Orthop Relat Res. 2005 Jun;(435):96-105 [PMID: 15930926]
  67. IEEE Trans Med Imaging. 1985;4(4):200-7 [PMID: 18243972]
  68. Osteoarthritis Cartilage. 2012 Aug;20(8):837-45 [PMID: 22548796]
  69. J Bone Joint Surg Am. 2003;85-A Suppl 2:17-24 [PMID: 12721341]
  70. J Magn Reson. 2007 Oct;188(2):191-5 [PMID: 17689121]
  71. Clin Orthop Relat Res. 2001 Oct;(391 Suppl):S26-33 [PMID: 11603710]
  72. J Magn Reson. 2010 Nov;207(1):42-52 [PMID: 20813569]
  73. Philos Trans R Soc Lond B Biol Sci. 1975 Jul 17;271(912):293-313 [PMID: 239424]
  74. J Bone Joint Surg Am. 2004 Mar;86(3):455-64 [PMID: 14996869]
  75. PM R. 2012 May;4(5 Suppl):S68-74 [PMID: 22632705]
  76. Osteoarthritis Cartilage. 2006 Feb;14(2):101-13 [PMID: 16188468]
  77. J Magn Reson. 2008 Aug;193(2):207-9 [PMID: 18502158]
  78. Magn Reson Med. 1996 Nov;36(5):665-73 [PMID: 8916016]
  79. J Bone Joint Surg Am. 1993 Apr;75(4):532-53 [PMID: 8478382]
  80. Arthritis Res Ther. 2005;7(1):R156-65 [PMID: 15642136]
  81. J Magn Reson. 2000 Jan;142(1):24-31 [PMID: 10617432]
  82. Instr Course Lect. 1998;47:477-86 [PMID: 9571449]

Grants

  1. I 652/Austrian Science Fund FWF
  2. I 690/Austrian Science Fund FWF
  3. P 25246/Austrian Science Fund FWF
Review
Article has an altmetric score of 1

Word Cloud

Created with Highcharts 10.0.0MRcartilageimagingsodiumstudiesSodiumrepairtissuepatientsosteoarthritisCartilageManyprovednoninvasivecandirectlydetermineGAGcontentplayscentralrolehomeostasisNewtechnicaldevelopmentsrecentdecadehelpedtransfermethodvitropre-clinicalvivoalreadyappliedevaluationvarioussurgerytechniquesshowedtechniquehelpfulassessmentstatusalsopredictiveHoweverduelowdetectablesignalstillchallenginghardwaresoftwareimprovementsnecessarytranslatingclinicalpracticepreferably3TsystemsImagingArticularPathologiesOsteoarthritisRepair

Similar Articles

Cited By