Nasal type NK/T-cell lymphoma - diagnosis and treatment difficulties.

N H Hamidah, Siti Shahrom, M A Siti Aishah, S Das, B S Gendeh, S A W Fadilah
Author Information
  1. N H Hamidah: Departments of Pathology, Haematology and Histopatology Units, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
  2. Siti Shahrom: Departments of Pathology, Haematology and Histopatology Units, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
  3. M A Siti Aishah: Departments of Pathology, Haematology and Histopatology Units, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
  4. S Das: Departments of Anatomy, Haematology and Histopatology Units, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
  5. B S Gendeh: Departments of Otorhinolaryngology, Haematology and Histopatology Units, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
  6. S A W Fadilah: Departments of Medicine, Haematology and Histopatology Units, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.

Abstract

Primary nasal lymphomas are rare. One of the most common cellular subtypes in the Asian population is natural killer (NK)/T-cell lymphoma (NKTL) with a high association of EBV. We report a case of a 42-year-old female, who presented with a worsening sore throat, odynophagia, dysphagia to solid food due to oropharyngeal ulcers and bilateral nasal blockage and recurrent fever for the past two weeks prior to admission. Physical examination revealed ulcers over the soft palate with nasopharyngeal slough. Computerized Tomography (CT) scan of the neck showed nasopharyngeal abscess with bilateral maxillary ethnoidal sinusitis. The diagnostic and management challenge is discussed.

MeSH Term

Adult
Candidiasis
Female
Herpesvirus 4, Human
Humans
Killer Cells, Natural
Lymphoma, Extranodal NK-T-Cell
Lymphoma, T-Cell
Nasopharyngeal Neoplasms
Plasmapheresis
Tomography, X-Ray Computed

Word Cloud

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