Detecting influential observations in a model-based cluster analysis.

Liesbeth Bruckers, Geert Molenberghs, Geert Verbeke, Helena Geys
Author Information
  1. Liesbeth Bruckers: 1 I-BioStat, Universiteit Hasselt, Hasselt, Belgium.
  2. Geert Molenberghs: 1 I-BioStat, Universiteit Hasselt, Hasselt, Belgium.
  3. Geert Verbeke: 1 I-BioStat, Universiteit Hasselt, Hasselt, Belgium.
  4. Helena Geys: 3 Janssen Pharmaceutica, Beerse, Belgium.

Abstract

Finite mixture models have been used to model population heterogeneity and to relax distributional assumptions. These models are also convenient tools for clustering and classification of complex data such as, for example, repeated-measurements data. The performance of model-based clustering algorithms is sensitive to influential and outlying observations. Methods for identifying outliers in a finite mixture model have been described in the literature. Approaches to identify influential observations are less common. In this paper, we apply local-influence diagnostics to a finite mixture model with known number of components. The methodology is illustrated on real-life data.

Keywords

MeSH Term

Algorithms
Animals
Biostatistics
Brain
Cluster Analysis
Computer Simulation
Electroencephalography
Humans
Likelihood Functions
Models, Statistical
Nonlinear Dynamics
Pharmacokinetics
Psychotropic Drugs
Rats

Chemicals

Psychotropic Drugs

Word Cloud

Created with Highcharts 10.0.0mixturemodelclusteringdatamodel-basedinfluentialobservationsfinitemodelsFiniteusedpopulationheterogeneityrelaxdistributionalassumptionsalsoconvenienttoolsclassificationcomplexexamplerepeated-measurementsperformancealgorithmssensitiveoutlyingMethodsidentifyingoutliersdescribedliteratureApproachesidentifylesscommonpaperapplylocal-influencediagnosticsknownnumbercomponentsmethodologyillustratedreal-lifeDetectingclusteranalysisLocalinfluence

Similar Articles

Cited By