Rei Shibata, Noriyuki Ouchi, Koji Ohashi, Toyoaki Murohara
Author Information
Rei Shibata: Department of Advanced Cardiovascular Therapeutics, Nagoya University Graduate School of Medicine, Nagoya, Japan. Electronic address: rshibata@med.nagoya-u.ac.jp.
Noriyuki Ouchi: Department of Molecular Cardiovascular Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Koji Ohashi: Department of Molecular Cardiovascular Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Toyoaki Murohara: Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Obesity leads to the development of cardiovascular diseases. Adipose tissue produces various bioactive molecules, also known as adipokines, and imbalanced production of adipokines contributes to the pathogenesis of obesity-linked metabolic and cardiovascular complications. Some adipokines such as adiponectin exert salutary actions on cardiovascular and metabolic disorders. Recent research has been conducted to identify poorly-characterized adipokines involved in cardiovascular regulation. In this review, we focus on the protective role of novel adipokines that are of current interest in the field of cardiology.
