Pelvic Radiation and Normal Tissue Toxicity.

Sarah Nicholas, Linda Chen, Amanda Choflet, Amanda Fader, Zachary Guss, Sarah Hazell, Daniel Y Song, Phuoc T Tran, Akila N Viswanathan
Author Information
  1. Sarah Nicholas: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, MD. Electronic address: snicho22@jhmi.edu.
  2. Linda Chen: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, MD.
  3. Amanda Choflet: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, MD.
  4. Amanda Fader: Division of Gynecologic Oncology, Johns Hopkins School of Medicine, Baltimore, MD.
  5. Zachary Guss: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, MD.
  6. Sarah Hazell: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, MD.
  7. Daniel Y Song: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, MD.
  8. Phuoc T Tran: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, MD.
  9. Akila N Viswanathan: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, MD.

Abstract

Radiation is a component of treatment for many pelvic malignancies, most often originating in the gynecologic, gastrointestinal, and genitourinary systems. Therefore, the management of acute and long-term side effects is an important part of practice as a radiation oncologist, and limiting morbidity is a primary goal. Toxicities vary and are dependent on treatment techniques. Advances in radiation delivery, imaging, and knowledge of underlying biologic determinants of radiation-induced normal tissue toxicity can guide treatment of acute and long-term side effects from pelvic radiation.

MeSH Term

Humans
Organs at Risk
Pelvic Neoplasms
Pelvis
Radiation Injuries

Word Cloud

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