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Diabetic medicine : a journal of the British Diabetic Association
04, 2020;37 (4): 532-544.

Is it possible to constantly and accurately monitor blood sugar levels, in people with Type 1 diabetes, with a discrete device (non-invasive or invasive)?

P Avari, M Reddy, N Oliver
Author Information
  1. P Avari: Division of Diabetes, Endocrinology and Metabolism, Faculty of Medicine, Imperial College, London, UK. ORCID
  2. M Reddy: Division of Diabetes, Endocrinology and Metabolism, Faculty of Medicine, Imperial College, London, UK.
  3. N Oliver: Division of Diabetes, Endocrinology and Metabolism, Faculty of Medicine, Imperial College, London, UK. ORCID
PMID: 30803028 DOI: 10.1111/dme.13942

Abstract

Real-time continuous glucose monitors using subcutaneous needle-type sensors continue to develop. The limitations of currently available systems, however, include time lag behind changes in blood glucose, the invasive nature of such systems, and in some cases, their accuracy. Non-invasive techniques have been developed, but, to date, no commercial device has been successful. A key research priority for people with Type 1 diabetes identified by the James Lind Alliance was to identify ways of monitoring blood glucose constantly and accurately using a discrete device, invasive or non-invasive. Integration of such a sensor is important in the development of a closed-loop system and the technology must be rapid, selective and acceptable for continuous use by individuals. The present review provides an update on existing continuous glucose-sensing technologies, and an overview of emergent techniques, including their accuracy and limitations.

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MeSH Term

Biosensing Techniques
Blood Glucose
Blood Glucose Self-Monitoring
Diabetes Mellitus, Type 1
Equipment Design
Equipment and Supplies
Glycemic Control
Humans
Monitoring, Physiologic

Chemicals

Blood Glucose
Journal Article Review
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