Mingmei Du: Department of Infection Management and Disease Control, Chinese PLA General Hospital, 28 Fuxing Rd, Haidian District, Beijing, 100853, China.
Bowei Liu: Department of Infection Management and Disease Control, Chinese PLA General Hospital, 28 Fuxing Rd, Haidian District, Beijing, 100853, China.
Meng Li: Department of Hematology, Chinese PLA General Hospital, Beijing, China.
Jingui Cao: Department of Infection Control, Air Force General Hospital, Beijing, China.
Ding Liu: Department of Infection Control, Daping Hospital, Chongqing, China.
Zhigang Wang: Department of Infection Control, The Army General Hospital, Beijing, China.
Qiongshu Wang: Department of Infection Control, Wuhan General Hospital, Wuhan, China.
Pengyun Xiao: Department of Disease Prevent and Control, Jinan General Hospital, Jinan, China.
Xinling Zhang: Department of Infection Control, Lanzhou General Hospital, Lanzhou, China.
Yanxin Gao: Department of Disease Prevent and Control, Urumqi General Hospital, Urumqi, China.
Hua Zeng: Department of Infection Control, Fuzhou General Hospital, Fuzhou, China.
Jing Yang: Department of Infection Control, ShenYang General Hospital, ShenYang, China.
Xiaoli Xu: Department of Infection Control, Nanjing General Hospital, Nanjing, China.
Yi Huang: Department of Infection Management, Changhai Hospital, Shanghai, China.
Qun Zhang: Department of Infection Management, Changzheng Hospital, Shanghai, China.
Bo Zhang: Department of Infection Control, Xinan Hospital, Chongqing, China.
Wei Chen: Department of Infection Control, Xinqiao Hospital, Chongqing, China.
Jieran Shi: Department of Infection Control, Xijing Hospital, Xian, China.
Shanhong Fan: Department of Infection Control, Tangdu Hospital, Xian, China.
Fuxiang Zhang: Department of Infection Control, General Hospital of the PLA Rocket Force, Beijing, China.
Jinyan Yang: Department of Infection Management and Disease Control, Hainan Hospital, Sanya, China.
Huining Yang: Department of Infection Control, The Armed Police General Hospital, Beijing, China.
Zhaoxia Ding: Department of Infection Control, 81 Hospital of PLA, Nanjing, China.
Haifeng Li: Department of Infection Control, 202 Hospital of PLA, Shenyang, China.
Sha Xiao: Department of Infection Control, 211 Hospital of PLA, Haerbin, China.
Suping Ran: Department of Infection Control, 306 Hospital of PLA, Beijing, China.
Hongyan Zhai: Department of Infection Control, 307 Hospital of PLA, Beijing, China.
Fang Wang: Department of Infection Control, 309 Hospital of PLA, Beijing, China.
Yubin Xing: Department of Infection Management and Disease Control, Chinese PLA General Hospital, 28 Fuxing Rd, Haidian District, Beijing, 100853, China.
Jijiang Suo: Department of Infection Management and Disease Control, Chinese PLA General Hospital, 28 Fuxing Rd, Haidian District, Beijing, 100853, China.
Yunxi Liu: Department of Infection Management and Disease Control, Chinese PLA General Hospital, 28 Fuxing Rd, Haidian District, Beijing, 100853, China. 1425628298@qq.com.
BACKGROUND: Colorectal surgery is associated with high rates of surgical site infection (SSI). We investigated SSI in radical resection of colon or rectal carcinoma and its epidemiological distribution in 26 hospitals in China. METHODS: We conducted prospective surveillance of patients who underwent radical resection of colon or rectal carcinoma in 26 selected hospitals from January 2015 to June 2016.An information system monitored all of the surgical inpatients. Infection control professionals observed the inpatients with suspected SSI who had been screened by the system at the bedside. The infection status of the incisions was followed up by telephone 1 month after the operation. RESULTS: In total, 5729 patients were enrolled for the two operations; SSIs occurred in 206 patients, and the infection rate was 3.60%. The incidence of SSI after radical resection of rectal carcinoma (5.12%; 119/2323) was 2.1 times higher than that after radical resection of colon carcinoma (2.55%; 87/3406) (P < 0.0001). Additionally, in the colon versus rectal groups, the rate of superficial incisional SSI was 0.94% versus 2.28% (P < 0.0001), the rate of deep incisional SSI was 0.56% versus 1.11% (P = 0.018), and the rate of organ space SSI was 1.06% versus 1.72% (P = 0.031), respectively. The most common pathogens causing SSIs after radical resection of colon carcinoma were Escherichia coli (21/38) and Pseudomonas aeruginosa (5/38). Escherichia coli (24/65) and Enterococcus spp. (14/65) were the two most common pathogens in the rectal group. The multivariate logistic regression analysis showed that only the operating time and number of hospital beds were common independent risk factors for SSIs after the two types of surgery. CONCLUSION: This multicenter study showed that there were significant differences in the incidence of SSIs, three types of SSIs, and some risk factors between radical resection of colon carcinoma and rectal carcinoma.
