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Nursing
Mar, 2020;50 (3): 32-39.

Nonalcoholic fatty liver disease: What nurses need to know.

Vincent M Vacca
Author Information
  1. Vincent M Vacca: Vincent M. Vacca, Jr., is an associate lecturer at the University of Massachusetts in Boston, Mass., and a member of the Nursing2020 editorial board.
PMID: 32068703 DOI: 10.1097/01.NURSE.0000654028.01550.56

Abstract

Nonalcoholic fatty liver disease (NAFLD) is defined as storage of excess fat in the liver not caused by heavy alcohol consumption. Nonalcoholic steatohepatitis is the severe form of NAFLD. This article discusses causes, diagnosis, and nursing interventions for patients with either disorder.

References

  1. National Institute of Diabetes and Digestive and Kidney Disease. Definition & Facts of NAFLD & NASH. 2016. www.niddk.nih.gov/health-information/liver-disease/nafld-nash/definition-facts.
  2. Sheth SG, Chopra S. Epidemiology, clinical features, and diagnosis of nonalcoholic fatty liver disease in adults. UpToDate. 2018. www.uptodate.com.
  3. Sharma B, Savio J. Nonalcoholic steatohepatitis. StatPearls [Internet]. 2019. www.ncbi.nlm.nih.gov/books/NBK470243.
  4. Sayiner M, Lam B, Golabi P, Younossi ZM. Advances and challenges in the management of advanced fibrosis in nonalcoholic steatohepatitis. Therap Adv Gastroenterol. 2018;11:17.
  5. Sao R, Aronow WS. Association of non-alcoholic fatty liver disease with cardiovascular disease and subclinical atherosclerosis. Arch Med Sci. 2018;14(6):1233–1244.
  6. Sharp KPH, Schultz M, Coppell KJ. Is non-alcoholic fatty liver disease a reflection of what we eat or simply how much we eat. JGH Open. 2018;2(2):59–74.
  7. Lucas C, Lucas G, Lucas N, Krzowska-Firych J, Tomasiewicz K. A systematic review of the present and future of non-alcoholic fatty liver disease. Clin Exp Hepatol. 2018;4(3):165–174.
  8. Advance Healthcare Network. Non-alcoholic fatty liver disease: an overview of key concepts for nurses. www.advanceweb.com. [e-pub November 17, 2014]
  9. National Heart Lung, and Blood Institute. Metabolic syndrome. www.nhlbi.nih.gov/health-topics/metabolic-syndrome.
  10. Meigs JB. Metabolic syndrome (insulin resistance syndrome or syndrome X). UpToDate. 2019. www.uptodate.com.
  11. Mak LY, Cruz-Ramón V, Chinchilla-López P, et al. Global epidemiology, prevention, and management of hepatocellular carcinoma. Am Soc Clin Oncol Educ Book. 2018;38:262–279.
  12. Stahl EC, Haschak MJ, Popovic B, Brown BN. Macrophages in the aging liver and age-related liver disease. Front Immunol. 2018;9:2795.
  13. Albhaisi S, Issa D, Alkhouri N. Non-alcoholic fatty liver disease: a pandemic disease with multisystem burden. Hepatobiliary Surg Nutr. 2018;7(5):389–391.
  14. Wisocky J, Paul S. The rising incidence of nonalcoholic fatty liver disease. Nurse Pract. 2017;42(7):14–20.
  15. Danford CJ, Yao ZM, Jiang ZG. Non-alcoholic fatty liver disease: a narrative review of genetics. J Biomed Res. 2018;32(5):389–400.
  16. Kudaravalli P, Savio J. Nonalcoholic fatty liver. StatPearls [Internet]. 2019. www.ncbi.nlm.nih.gov/books/NBK541033.
  17. Chalasani N, Younossi Z, Lavine JE, et al. The diagnosis and management of nonalcoholic fatty liver disease: practice guidance from the American Association for the Study of Liver Diseases. Hepatology. 2018;67(1):328–357.
  18. Polewiczowska B, Aldulaimi D. Recent advances in non-alcoholic fatty liver disease. Gastroenterol Hepatol Bed Bench. 2018;11(4):363–365.
  19. Goldberg E, Chopra S. Cirrhosis in adults: etiologies, clinical manifestations, and diagnosis. UpToDate. 2018. www.uptodate.com.
  20. Yao H, Qiao YJ, Zhao YL, et al. Herbal medicines and nonalcoholic fatty liver disease. World J Gastroenterol. 2016;22(30):6890–6905.
  21. El-Gohary M, Moore M, Roderick P, et al. Local care and treatment of liver disease (LOCATE)—a cluster-randomized feasibility study to discover, assess and manage early liver disease in primary care. PLoS One. 2018;13(12):e0208798.
  22. Pavlov CS, Casazza G, Nikolova D, et al. Transient elastography for measurement of liver fibrosis and cirrhosis in people with alcoholic liver disease. Cochrane. 2015. www.cochrane.org.
  23. Fibrosis-4 (FIB-4) calculator. Hepatitis C Online. www.hepatitisc.uw.edu/page/clinical-calculators/fib-4.
  24. Danford CJ, Connelly MA, Shalaurova I, et al. A pathophysiologic approach combining genetics and insulin resistance to predict the severity of nonalcoholic fatty liver disease. Hepatol Commun. 2018;2(12):1467–1478.
  25. Isabela Andronescu C, Roxana Purcarea M, Aurel Babes P. The role of noninvasive tests and liver biopsy in the diagnosis of nonalcoholic fatty liver disease. J Med Life. 2018;11(3):243–246.
  26. Zelber-Sagi S, Godos J, Salomone F. Lifestyle changes for the treatment of nonalcoholic fatty liver disease: a review of observational studies and intervention trials. Therap Adv Gastroenterol. 2016;9(3):392–407.
  27. Chopra S, Lai M. Management of nonalcoholic fatty liver disease in adults. UpToDate. 2019. www.uptodate.com.
  28. Lee HY, Jun DW, Kim HJ, et al. Ezetimibe decreased nonalcoholic fatty liver disease activity score but not hepatic steatosis. Korean J Intern Med. 2019;34(2):296–304.
  29. Hearn C, Ellington BJ, Jones R. The role of the nurse practitioner in the management of nonalcoholic fatty liver disease. Gastroenterol Nurs. 2018;41(5):424–426.
  30. Porth CS. Essentials of Pathophysiology: Concepts of Altered Health States. 4th ed. Philadelphia, PA: Wolters Kluwer; 2014.
  31. Patel R, Gossman W. Alcoholic liver disease. StatPearls [Internet]. 2019. www.ncbi.nlm.nih.gov/books/NBK546632.
  32. Sterling RK, Lissen E, Clumeck N, et al. Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV co-infection. Hepatology. 2006;43(6):1317–1325.

MeSH Term

Humans
Metabolic Syndrome
Non-alcoholic Fatty Liver Disease
Nursing Assessment
Nursing Diagnosis
Patient Education as Topic
Risk Factors
Severity of Illness Index
Journal Article
Article has an altmetric score of 3

Word Cloud

Created with Highcharts 10.0.0NonalcoholicliverfattyNAFLDdiseasedefinedstorageexcessfatcausedheavyalcoholconsumptionsteatohepatitissevereformarticlediscussescausesdiagnosisnursinginterventionspatientseitherdisorderdisease:nursesneedknow

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