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Contact dermatitis
Oct, 2020;83 (4): 296-300.

Compositae sensitization in Danish children and adolescents.

Evy Paulsen, Klaus E Andersen
Author Information
  1. Evy Paulsen: Department of Dermatology and Allergy Centre, Odense University Hospital, University of Southern Denmark, Odense, Denmark. ORCID
  2. Klaus E Andersen: Department of Dermatology and Allergy Centre, Odense University Hospital, University of Southern Denmark, Odense, Denmark. ORCID
PMID: 32542786 DOI: 10.1111/cod.13639

Abstract

BACKGROUND: Compositae plant sensitization in children is relatively frequent. From 1995-2006, we found a prevalence of 1.8% sesquiterpene lactone (SL) mix/parthenolide patch test positives among consecutive eczema patients <18 years.
OBJECTIVES: To report the results of patch test screening for Compositae sensitization in patients <18 years in the last 13 years.
METHODS: Children and adolescents <18 years, diagnosed with Compositae sensitization between 2007 and 2019, were included.
RESULTS: Among 388 children tested, 12 (3%) were Compositae-sensitized, and 11 (2.8%) had positive reactions to SL mix. Compositae mix 5% pet. elicited positive reactions in six of seven patients tested, and dandelion extract 2.5% pet. in six of 10 patients tested. The mean age of the five girls and seven boys was 9.4 years and 11.7 years, respectively. Eleven children had a personal and one a family history of atopy, and 11 children had hand eczema. Only two were mono-sensitized to Compositae.
CONCLUSIONS: SL mix is a suitable screening agent among children and adolescents in our area, well supplemented with Compositae mix 5% and dandelion extract. The study emphasizes the importance of Compositae screening in children with a personal and/or family history of atopy, hand eczema or widespread airborne dermatitis, summer exacerbation, and plant exposure.

Keywords

Asteraceae Compositae Compositae mix allergic contact dermatitis children dandelion patch testing sesquiterpene lactone mix

References

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MeSH Term

Adolescent
Allergens
Asteraceae
Child
Denmark
Dermatitis, Allergic Contact
Female
Humans
Male
Plant Extracts
Sesquiterpenes

Chemicals

Allergens
Plant Extracts
Sesquiterpenes
parthenolide
Journal Article

Word Cloud

Created with Highcharts 10.0.0CompositaechildrenmixsensitizationpatientsSLpatcheczema<18 yearsscreeningadolescentstested115%dandelionplant8%sesquiterpenelactonetestamong2positivereactionspetsixsevenextractpersonalfamilyhistoryatopyhanddermatitisBACKGROUND:relativelyfrequent1995-2006foundprevalence1mix/parthenolidepositivesconsecutiveOBJECTIVES:reportresultslast13 yearsMETHODS:Childrendiagnosed20072019includedRESULTS:Among388123%Compositae-sensitizedelicited10meanagefivegirlsboys94 years7 yearsrespectivelyElevenonetwomono-sensitizedCONCLUSIONS:suitableagentareawellsupplementedstudyemphasizesimportanceand/orwidespreadairbornesummerexacerbationexposureDanishAsteraceaeallergiccontacttesting

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