Eclipsed Functional Mitral Regurgitation Destabilizing Hypertrophic Cardiomyopathy: An Unusual Case Treated With MitraClip.

Catherine Bourque, Marina Dijos, Lionel Leroux, Louis Labrousse, Alexandre Metras, Matthieu Michaud, Marie Hébert, Patricia Réant, Stéphane Lafitte
Author Information
  1. Catherine Bourque: CHU de Bordeaux, Service médico-chirurgical de valvulopathies et cardiomyopathies, chirurgie cardiaque adulte, cardiologie interventionnelle structurelle adulte, F-33000, Bordeaux, France.
  2. Marina Dijos: CHU de Bordeaux, Service médico-chirurgical de valvulopathies et cardiomyopathies, chirurgie cardiaque adulte, cardiologie interventionnelle structurelle adulte, F-33000, Bordeaux, France.
  3. Lionel Leroux: CHU de Bordeaux, Service médico-chirurgical de valvulopathies et cardiomyopathies, chirurgie cardiaque adulte, cardiologie interventionnelle structurelle adulte, F-33000, Bordeaux, France.
  4. Louis Labrousse: CHU de Bordeaux, Service médico-chirurgical de valvulopathies et cardiomyopathies, chirurgie cardiaque adulte, cardiologie interventionnelle structurelle adulte, F-33000, Bordeaux, France.
  5. Alexandre Metras: CHU de Bordeaux, Service médico-chirurgical de valvulopathies et cardiomyopathies, chirurgie cardiaque adulte, cardiologie interventionnelle structurelle adulte, F-33000, Bordeaux, France.
  6. Matthieu Michaud: CHU de Bordeaux, Service médico-chirurgical de valvulopathies et cardiomyopathies, chirurgie cardiaque adulte, cardiologie interventionnelle structurelle adulte, F-33000, Bordeaux, France.
  7. Marie Hébert: CHU de Bordeaux, Service médico-chirurgical de valvulopathies et cardiomyopathies, chirurgie cardiaque adulte, cardiologie interventionnelle structurelle adulte, F-33000, Bordeaux, France.
  8. Patricia Réant: CHU de Bordeaux, Service médico-chirurgical de valvulopathies et cardiomyopathies, chirurgie cardiaque adulte, cardiologie interventionnelle structurelle adulte, F-33000, Bordeaux, France.
  9. Stéphane Lafitte: CHU de Bordeaux, Service médico-chirurgical de valvulopathies et cardiomyopathies, chirurgie cardiaque adulte, cardiologie interventionnelle structurelle adulte, F-33000, Bordeaux, France.

Abstract

MitraClip (Abbott Laboratories, Abbott Park, IL) is validated in high-risk patients with severe degenerative mitral regurgitation (MR); however, it is not well established for functional MR in hypertrophic cardiomyopathy (HCM). We share a case of a 68-year-old man with HCM hospitalized for multiple incidents of acute pulmonary edema caused by a dynamic MR and successfully treated with the MitraClip device. Novel teaching points emerging from this case are that MRs in HCM can often be explained by mixed mechanisms, and properly identifying the MR mechanism is essential to choose optimal treatment. Furthermore, MitraClip can simultaneously treat MR secondarily to annular dilation and systolic anterior motion.

References

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  2. Eur J Heart Fail. 2020 Feb;22(2):228-240 [PMID: 31919938]
  3. Heart. 2020 May;106(10):716-723 [PMID: 32054671]
  4. J Am Coll Cardiol. 2020 May 5;75(17):2236-2270 [PMID: 32068084]

Word Cloud

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